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结构效度支持使用一种新型基于平板电脑的神经认知评估工具，用于评估来自美国弱势社区的围产期感染 HIV 的青少年和年轻成人。

Construct Validity Supports Use of a Novel, Tablet-Based Neurocognitive Assessment for Adolescents and Young Adults Affected by Perinatal HIV from Vulnerable Communities in the United States.

机构信息

HIV Center for Clinical and Behavioral Studies, Columbia University and New York State Psychiatric Institute, New York, NY, USA.

New York State Psychiatric Institute, Psychiatry, New York, NY, USA.

出版信息

AIDS Behav. 2021 Apr;25(4):1185-1191. doi: 10.1007/s10461-020-03099-3. Epub 2020 Nov 12.

DOI:10.1007/s10461-020-03099-3
PMID:33180252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7979459/
Abstract

Construct validity of novel tablet-based neurocognitive tests (in the NeuroScreen app) measuring processing speed, working memory, and executive functioning in adolescents and young adults (AYA) living with perinatally-acquired HIV (PHIV) and perinatal HIV-exposure without infection (PHEU) was examined. Sixty-two AYA (33 PHIV, 29 PHEU) were recruited from an ongoing longitudinal study (CASAH) in New York City. Medium to large and statistically significant correlations were found between NeuroScreen and gold standard, paper-and-pencil tests of processing speed, working memory, and executive functioning. Results provide partial support for NeuroScreen as an alternative to cumbersome paper-and-pencil tests for assessing neurocognition among HIV-affected AYA.

摘要

新型基于平板电脑的神经认知测试（在 NeuroScreen 应用程序中）在患有围产期获得性 HIV（PHIV）和围产期 HIV 暴露但未感染（PHEU）的青少年和年轻成人（AYA）中测量处理速度、工作记忆和执行功能的结构效度进行了检验。从纽约市一项正在进行的纵向研究（CASAH）中招募了 62 名 AYA（33 名 PHIV，29 名 PHEU）。NeuroScreen 与处理速度、工作记忆和执行功能的金标准纸笔测试之间存在中等至较大且具有统计学意义的相关性。研究结果部分支持 NeuroScreen 作为一种替代繁琐的纸笔测试的方法，用于评估受 HIV 影响的 AYA 的神经认知功能。

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