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[通过缩宫素敏感性试验对使用PGE2进行择期引产的结局样本进行鉴别]

[Differentiation of an outcome sample in elective labor induction with PGE2 by the oxytocin sensitivity test].

作者信息

Egarter C, Schurz B, Schmidl S, Husslein P

机构信息

I. Universitäts-Frauenklinik, Wien.

出版信息

Wien Klin Wochenschr. 1987 Sep 25;99(18):642-6.

PMID:3318145
Abstract

The goal of the present study was to evaluate whether the implementation of an oxytocin sensitivity test in addition to pelvic scoring would improve prediction of successful induction and could lead to a further reduction in the already low rate of protracted labour and operative deliveries in cases of elective induction by means of prostaglandin (PG) E2 tablets. In order to establish the optimal dosage we compared the endocervical application of 1.5 mg PG E2 with 3 mg intravaginally. Out of 158 women without risk factors examined at term 73.5% decided to have labour induced. In the induction groups given endocervical or intravaginal PG E2 the delivery intervals were significantly shorter and the rate of operative deliveries was reduced. In comparison with those women who decided to await spontaneous onset of labour, the fetal outcome was, however, the same. The endocervical application of 1.5 mg PG E2 did not prove any better than 3 mg given intravaginally. The performance of a pretherapeutic oxytocin sensitivity test yielded additional information about the chances of inducing labour successfully. The results confirmed the efficacy and acceptance of this method of inducing labour.

摘要

本研究的目的是评估除骨盆评分外,实施缩宫素敏感性试验是否能改善对引产成功的预测,并能否进一步降低在使用前列腺素(PG)E2片进行择期引产时本已较低的产程延长和手术分娩发生率。为确定最佳剂量,我们比较了宫颈内应用1.5mg PGE2与阴道内应用3mg PGE2的效果。在158名足月检查无危险因素的女性中,73.5%决定引产。在给予宫颈内或阴道内PGE2的引产组中,分娩间隔明显缩短,手术分娩率降低。然而,与那些决定等待自然临产的女性相比,胎儿结局相同。宫颈内应用1.5mg PGE2并不比阴道内应用3mg效果更好。治疗前缩宫素敏感性试验的实施产生了关于成功引产几率的额外信息。结果证实了这种引产方法的有效性和可接受性。

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