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COVID-19 肺炎康复后无既往残疾的患者的肌肉力量和身体机能。

Muscle Strength and Physical Performance in Patients Without Previous Disabilities Recovering From COVID-19 Pneumonia.

机构信息

From the Respiratory Rehabilitation of the Institute of Lumezzane, Istituti Clinici Scientifici Maugeri IRCCS, Brescia, Italy (MP, CS, MS, LB, M. Vitacca); Department of Neurosciences, Biomedicine and Movement Sciences, Università di Verona, Verona, Italy (M. Venturelli); Department of Rehabilitation Sciences, University Hospitals Gasthuisberg, Leuven, Belgium (TT); Respiratory Division, KU Leuven, Leuven, Belgium (TT); and Respiratory Rehabilitation of the Institute of Montescano, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy (NA).

出版信息

Am J Phys Med Rehabil. 2021 Feb 1;100(2):105-109. doi: 10.1097/PHM.0000000000001641.

Abstract

In this cross-sectional study, we evaluated skeletal muscle strength and physical performance (1-min sit-to-stand and short physical performance battery tests), dyspnea, fatigue, and single-breath counting at discharge from a postacute COVID department, in patients recovering from COVID-19 pneumonia who had no locomotor disability before the infection.Quadriceps and biceps were weak in 86% and 73% of the patients, respectively. Maximal voluntary contraction for quadriceps was 18.9 (6.8) kg and for biceps 15.0 (5.5) kg (i.e., 54% and 69% of the predicted normal value, respectively). The number of chair rises in the 1-min sit-to-stand test was 22.1 (7.3 corresponding to 63% of the predicted normal value), whereas the short physical performance battery score was 7.9 (3.3 corresponding to 74% of the predicted normal value). At the end of the 1-min sit-to-stand test, 24% of the patients showed exercise-induced desaturation. The single-breath counting count was 35.4 (12.3) corresponding to 72% that of healthy controls. Mild-to-moderate dyspnea and fatigue were found during activities of daily living (Borg scale score, median value = 0.5 [0-2] and 1 [0-2]) and after the 1-min sit-to-stand (Borg scale score, median value = 3 [2-5] and 1 [0-3]). Significant correlations were observed between muscle strength and physical performance indices (R = 0.31-0.69).The high prevalence of impairment in skeletal muscle strength and physical performance in hospitalized patients recovering from COVID-19 pneumonia without previous locomotor disabilities suggests the need for rehabilitation programs after discharge.

摘要

在这项横断面研究中,我们评估了从急性 COVID 病房出院的 COVID-19 肺炎康复患者的骨骼肌力量和身体表现(1 分钟坐站和简短身体表现电池测试)、呼吸困难、疲劳和单次呼吸计数,这些患者在感染前没有运动障碍。分别有 86%和 73%的患者出现四肢无力。股四头肌和肱二头肌的最大自主收缩力分别为 18.9(6.8)kg 和 15.0(5.5)kg(即分别为预测正常值的 54%和 69%)。1 分钟坐站测试中,患者可坐站起 22.1(7.3,对应预测正常值的 63%),而简短身体表现电池测试评分为 7.9(3.3,对应预测正常值的 74%)。在 1 分钟坐站测试结束时,24%的患者出现运动诱导的血氧饱和度下降。单次呼吸计数为 35.4(12.3),对应健康对照组的 72%。在日常生活活动(Borg 量表评分,中位数=0.5[0-2]和 1[0-2])和 1 分钟坐站后(Borg 量表评分,中位数=3[2-5]和 1[0-3]),患者都存在轻度至中度呼吸困难和疲劳。肌肉力量和身体表现指标之间存在显著相关性(R=0.31-0.69)。在没有先前运动障碍的 COVID-19 肺炎住院康复患者中,骨骼肌力量和身体表现受损的高患病率表明出院后需要康复计划。

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