From the Department of Nuclear Medicine and PET/CT, Mahajan Imaging Centre.
Department of Neurology, Sir Ganga Ram Hospital, New Delhi, India.
Clin Nucl Med. 2021 Jan;46(1):e63-e64. doi: 10.1097/RLU.0000000000003379.
We report a case of 34-year-old woman presenting with complaints of abnormal posturing of hand and tonic-clonic seizures of few days' duration, which soon progressed to psychotic episodes and injuries secondary to fall/abnormal movements. She underwent F-FDG PET for a suspicion of encephalitis, which revealed increased FDG uptake in the bilateral parietotemporal lobes (right more than left), anterior cingulate cortex, bilateral basal ganglia, thalami, and cerebellum. This atypical pattern did not conform to any known pattern of encephalitis, which was later attributed to the presence of both anti-NMDAr and anti-GAD antibodies in blood and cerebrospinal fluid.
我们报告了一例 34 岁女性，她主诉手部姿势异常和数天的强直阵挛性癫痫发作，随后很快出现精神病发作和跌倒/异常运动引起的损伤。她因疑似脑炎接受 F-FDG PET 检查，结果显示双侧顶颞叶（右侧多于左侧）、前扣带回皮质、双侧基底节、丘脑和小脑的 FDG 摄取增加。这种非典型模式不符合任何已知的脑炎模式，后来归因于血液和脑脊液中存在抗 NMDAr 和抗 GAD 抗体。
