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18F-FDG PET/CT 诊断甲状旁腺功能亢进引起的意外棕色肿瘤检测。

Detection of Unexpected Brown Tumors Due to Hyperparathyroidism Diagnosed by 18F-FDG PET/CT.

机构信息

From the Division of Nuclear Medicine, University Hospitals Leuven, Leuven, Belgium.

出版信息

Clin Nucl Med. 2021 Jan;46(1):e16-e17. doi: 10.1097/RLU.0000000000003380.

DOI:10.1097/RLU.0000000000003380
PMID:33181751
Abstract

A 27-year-old man was called to receive a kidney transplant. The preoperative CT of the chest showed multiple osteolytic lesions, as well as a hypodense structure posterior in the right thyroid lobe. Blood analysis showed elevated parathyroid hormone, phosphorus, and alkaline phosphatase levels, with normal calcium and 25-OH-vitamin D. F-FDG PET/CT demonstrated generalized elevated FDG uptake in the bone (due to hyperparathyroidism), as well as multiple hypermetabolic focal lesions spread throughout the bone (fitting brown tumors). The nodule posterior of the right thyroid lobe showed an intense FDG uptake as well, suggestive of a parathyroid adenoma/hyperplasia. Histopathology confirmed the diagnosis.

摘要

一位 27 岁男性被召来接受肾移植。术前胸部 CT 显示多发溶骨性病变,以及右甲状腺叶后部的一个低密结构。血液分析显示甲状旁腺激素、磷和碱性磷酸酶水平升高,血钙和 25-OH-维生素 D 正常。F-FDG PET/CT 显示全身骨 FDG 摄取增加(由于甲状旁腺功能亢进),以及多处骨内高代谢局灶性病变(符合棕色瘤)。右甲状腺叶后部的结节也显示出强烈的 FDG 摄取,提示甲状旁腺腺瘤/增生。组织病理学证实了诊断。

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