Copeland J G, Stinson E B, Griepp R B, Shumway N E
Acta Chir Belg. 1977 May-Jun;76(3):387-92.
Increasing survival of cardiac allograft recipients has been noted with each year of the Stanford cardiac transplantation program. Current 1 year survival is 67%, compared with 22% 1 year survival in the first year of our program. Five factors are felt to be important in improving survival: 1 degree stringent recipient selection criteria, 2 degrees routine use of serial endomyocardial biopsies for the diagnosis of acute graft rejection, 3 degrees administration of rabbit antithymocyte globulin for the treatment of rejection, 4 degrees aggressive diagnosis and treatment of infectious complications, and 5 degrees reduction of the incidence of accelerated graft arteriosclerosis by appropriate prophylaxis.
斯坦福心脏移植项目开展至今，心脏移植受者的生存率逐年提高。目前1年生存率为67%，而在我们项目开展的第一年，1年生存率为22%。有五个因素被认为对提高生存率很重要：1. 严格的受者选择标准；2. 常规使用系列心内膜心肌活检来诊断急性移植物排斥反应；3. 使用兔抗胸腺细胞球蛋白治疗排斥反应；4. 积极诊断和治疗感染并发症；5. 通过适当的预防措施降低加速性移植物动脉硬化的发生率。
