Ulanova M A, Padiukov L N, Katosova L K, Tolkachev A M
Zh Mikrobiol Epidemiol Immunobiol. 1987 Sep(9):112-5.
IgA-antibodies to pneumococcal antigens were measured by enzyme immunoassay in saliva and nasal washings, obtained from 32 children aged 6 months to 14 years with acute pneumonia and from 25 healthy children aged 2.5-11 years. In the secretions of children with acute pneumonia an essential increase in the levels of IgA-antibodies in comparison with those observed in healthy children was detected. The levels of antibodies to pneumococci in saliva and in nasal washings were in direct correlation. These data are indicative of a protective role played, probably, by secretory antibodies at the portals of infection in pneumococcal pneumonia.
采用酶免疫分析法测定了32例6个月至14岁急性肺炎患儿以及25例2.5至11岁健康儿童唾液和鼻腔灌洗液中针对肺炎球菌抗原的IgA抗体。与健康儿童相比，急性肺炎患儿分泌物中IgA抗体水平显著升高。唾液和鼻腔灌洗液中肺炎球菌抗体水平呈正相关。这些数据表明，分泌型抗体可能在肺炎球菌肺炎感染门户发挥保护作用。
