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阿曼工业氯气暴露事件的临床特征和转归

Clinical Presentations and Outcomes of Industrial Chlorine Gas Exposure Incidence in Oman.

机构信息

Department of Emergency Medicine, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman.

出版信息

Prehosp Disaster Med. 2021 Feb;36(1):18-24. doi: 10.1017/S1049023X20001375. Epub 2020 Nov 13.

DOI:10.1017/S1049023X20001375
PMID:33183378
Abstract

OBJECTIVE

The main objective was to study different clinical presentations and outcomes of patients after acute industrial chlorine gas exposure in Oman with evaluation of overall incident management to help develop a chemical exposure incident protocol.

METHODS

This was a retrospective observational study of 15 patients exposed to chlorine gas after an accidental chlorine gas leak in a metal melting factory in Oman.

RESULTS

Six (40%) patients were admitted and nine (60%) patients were discharged from the emergency department (ED) after initial management. The important post-chlorine gas exposure clinical symptoms were eye irritation (66.6%), cough (73.3%), shortness of breath (40.0%), chest discomfort (66.6%), rhinorrhea (66.6%), dizziness (40.0%), vomiting (46.6%), sore throat (13.3%), and stridor (53.3%). Important signs included tachycardia (40.0%), tachypnea (40.0%), wheeze (20.0%), and use of accessory muscles for breathing (20.0%). Signs and symptoms of eye irritation, rhinorrhea, tachycardia, tachypnea, wheeze, and use of accessory muscles for breathing have shown significant correlation with outcome (admission) having P value of <.05.

CONCLUSION

In the presented acute chlorine gas exposure incidence, 15 exposed persons were brought to the ED, out of which six were admitted and nine were discharged after symptomatic treatment. Signs and symptoms of eye irritation, rhinorrhea, tachycardia, tachypnea, wheeze, and use of accessory muscles of breathing show significant relation with the outcome of admission.

摘要

目的

本研究旨在探讨阿曼急性工业氯气暴露患者的不同临床表现和转归,并评估整体事件管理情况,以期为化学暴露事件预案的制定提供参考。

方法

这是一项对阿曼一家金属熔炼厂氯气意外泄漏后 15 名氯气暴露患者的回顾性观察性研究。

结果

6 名(40%)患者入院,9 名(60%)患者在急诊科(ED)接受初始治疗后出院。氯气暴露后的重要临床症状包括眼部刺激(66.6%)、咳嗽(73.3%)、呼吸急促(40.0%)、胸部不适(66.6%)、流涕(66.6%)、头晕(40.0%)、呕吐(46.6%)、咽痛(13.3%)和喘鸣(53.3%)。重要体征包括心动过速(40.0%)、呼吸急促(40.0%)、哮鸣音(20.0%)和辅助呼吸肌使用(20.0%)。眼部刺激、流涕、心动过速、呼吸急促、哮鸣音和辅助呼吸肌使用等症状和体征与结局(入院)呈显著相关,P 值均<0.05。

结论

在本次急性氯气暴露事件中,15 名暴露者被送往急诊科,其中 6 名入院,9 名经对症治疗后出院。眼部刺激、流涕、心动过速、呼吸急促、哮鸣音和辅助呼吸肌使用等症状和体征与入院结局显著相关。

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