Friedman S E, Dubovsky E V, Dubovsky J, Alexander C B, Robinson C A, Sabbagh E A, Barnes G T, Fraser R G
Department of Radiology, University of Alabama at Birmingham 35233.
AJR Am J Roentgenol. 1987 Dec;149(6):1199-202. doi: 10.2214/ajr.149.6.1199.
Several methods are presently available for measuring the mineral content of bone. Those in widespread use include dual-photon absorptiometry and quantitative CT. The feasibility of using dual-energy digital chest radiography for determination of the mineral content of posterior ribs on digital chest images was studied by using a prototype unit. The results showed a significant difference in the mineral density of the posterior ribs of control subjects and those of patients who had osteoporosis (251.1 +/- 36 mg Ca2+/cm2 of rib vs 158.8 +/- 48 mg Ca2+/cm2, p less than or equal to .01) and a close correlation with values obtained by dual-photon absorptiometry of the lumbar spine (r = .77). The results suggest that this technique can provide an accurate assessment of the presence or absence of osteoporosis.
目前有几种方法可用于测量骨矿物质含量。广泛使用的方法包括双能光子吸收法和定量CT。使用一台原型设备研究了利用双能数字胸部X线摄影术测定数字胸部图像上后肋矿物质含量的可行性。结果显示，对照组受试者与骨质疏松症患者后肋的矿物质密度存在显著差异（后肋为251.1±36mg Ca2+/cm2，而患者为158.8±48mg Ca2+/cm2，p≤0.01），并且与通过腰椎双能光子吸收法获得的值密切相关（r = 0.77）。结果表明，该技术能够准确评估骨质疏松症的有无。
