Department of Pediatrics, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran; Hepatitis Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran; Fellowship of Pediatrics Gastroenterology, Pediatric Gastroenterology and Hepatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Pediatric Gastroenterology and Hepatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Clin Nutr ESPEN. 2020 Dec;40:237-241. doi: 10.1016/j.clnesp.2020.09.013. Epub 2020 Sep 23.
Allergic colitis (AC) is one of the most common etiologies of rectal bleeding in infants aged one to six months.
The aim of this study is to apply step-by-step dietary restrictions in the mother's diet or change of infant formula fed thereby, to evaluate the subsequent clinical response.
Sixty healthy infants whose clinical and evaluation results indicated proctocolitis in our outpatient gastroenterology clinic were included in this. They were divided into three groups according to the type of feeding; group 1 were exclusively breast fed, group 2 were exclusively formula fed and group 3 were fed with combination of both. In breast feeding women, discontinuation was allergenic food was studied in four stages; cow-related dairy products, soy, sesame and fast food (stage A), egg (stage B), corn, nuts and fish (stage C) and wheat (stage D).
Sixty newborns with age at symptom onset 3 days-20 days participated in the study. Up to the time of our initial evaluation, the mean age and weight of infants was 73.34 ± 1.00 day and 3292.71 ± 367.93 g, respectively. There was no significant difference in sex and the type of labor between the groups. Thirty-three infants had a history of eczema and the parents of 47 infants had a history of allergy, with the greatest prevalence in group one. Rectal bleeding in 50% of infants was halted after the elimination of allergenic feed in mother (15 in stage A, 8 in stage B and 7 in stage C). Ten infants needed extensive hydrolyzed formula and 20 needed amino acid-based formulas.
There is no need for immediate use of amino acid or extensive hydrolyzed formulas in the first stage of blood in stool, perhaps discontinuing allergenic food in mothers could be the primary measure.
过敏性结肠炎（AC）是 1-6 个月龄婴儿直肠出血的最常见病因之一。
本研究旨在通过逐步限制母亲饮食中的过敏原或改变婴儿配方奶，评估随后的临床反应。
本研究纳入了 60 名在我院门诊消化科就诊的具有直肠结肠炎临床表现和评估结果的健康婴儿。根据喂养方式将他们分为三组：组 1 为纯母乳喂养，组 2 为纯配方奶喂养，组 3 为混合喂养。在母乳喂养的母亲中，我们研究了停止食用过敏食物的四个阶段：与牛有关的奶制品、大豆、芝麻和快餐（阶段 A）、鸡蛋（阶段 B）、玉米、坚果和鱼（阶段 C）和小麦（阶段 D）。
60 名新生儿的发病年龄为 3 天至 20 天。在我们首次评估时，婴儿的平均年龄和体重分别为 73.34±1.00 天和 3292.71±367.93g。各组间性别和分娩方式无显著差异。33 名婴儿有湿疹病史，47 名婴儿的父母有过敏史，其中组 1 的患病率最高。在母亲停止食用过敏原后，50%的婴儿直肠出血停止（A 阶段 15 例，B 阶段 8 例，C 阶段 7 例）。10 名婴儿需要广泛水解配方奶，20 名婴儿需要氨基酸配方奶。
在便血的第一阶段，无需立即使用氨基酸或广泛水解配方奶，或许停止母亲的过敏原饮食可能是首要措施。
