Gas Conversion Department, Faculty of Petrochemicals, Iran Polymer and Petrochemical Institute, PO Box 14975-112, Tehran, Iran.
Department of Chemistry, School of Science, Alzahra University, Vanak, PO Box 1993891176, Tehran, Iran.
Sci Rep. 2020 Nov 12;10(1):19666. doi: 10.1038/s41598-020-76795-8.
In attempt to develop a biocompatible metal-free catalyst, a dendritic moiety was grown on chitosan through successive reactions with 2,4,6-trichloro-1,3,5-triazine and ethylenediamine. Subsequently, the terminal functional groups of the dendron were decorated with 1-methylimidazolium chloride. The catalyst was characterized with SEM, EDS, TGA, FTIR, XRD and mapping analysis. Then, the catalytic activity of the resultant composite was scrutinized for catalyzing Knoevenagel condensation and synthesis of xanthene derivatives in aqueous media under mild reaction condition. The results confirmed high activity of the catalyst, superior to ionic liquid free counterpart and bare chitosan. This observation was ascribed to the instinct catalytic activity of ionic liquid. Moreover, using control catalysts, it was confirmed that the presence of the dendritic moiety that could increase the content of ionic liquid on the backbone of the catalyst enhanced the catalytic activity.
为了开发一种生物相容性的无金属催化剂，通过与 2,4,6-三氯-1,3,5-三嗪和乙二胺的连续反应，在壳聚糖上生长出树枝状部分。随后，树枝状分子的末端官能团用 1-甲基咪唑氯进行了修饰。采用 SEM、EDS、TGA、FTIR、XRD 和mapping 分析对催化剂进行了表征。然后，研究了所得复合材料在温和反应条件下在水介质中催化 Knoevenagel 缩合和香豆素衍生物合成的催化活性。结果证实了该催化剂的高活性，优于无离子液体的对照物和裸露的壳聚糖。这一观察结果归因于离子液体的固有催化活性。此外，使用对照催化剂，证实了存在树枝状部分可以增加催化剂主链上离子液体的含量，从而提高了催化活性。
