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脊髓刺激治疗慢性疼痛综合征:实践管理中的注意事项综述。

Spinal Cord Stimulation for Chronic Pain Syndromes: A Review of Considerations in Practice Management.

机构信息

Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, TX.

Department of Anesthesiology, University of Texas Health Science Center, San Antonio, TX.

出版信息

Pain Physician. 2020 Nov;23(6):599-616.

Abstract

BACKGROUND

Chronic pain syndromes are clinically challenging to treat, and management with opioid medications is increasingly shown to be inappropriate and ineffective. Spinal cord stimulation (SCS) has been demonstrated across numerous high-quality and well-designed studies to be effective in treating various refractory chronic pain. The efficacy and overall success of SCS is highly dependent on compliance to and consideration of various practice patterns.

OBJECTIVE

This manuscript is intended to compile and present comprehensive recommendations for key SCS management principles including: a) patient selection criteria, b) efficacy of SCS for various conditions, c) discussion of SCS waveforms, d) trial and permanent implantation considerations, e) periprocedural management, and f) complications and adverse events.

STUDY DESIGN

An evidence-based narrative review.

METHODS

PubMed, Medline, Cochrane Library, prior systematic reviews, and reference lists were screened by 2 separate authors for all randomized trials, meta-analyses, and observational studies relevant to each of the aforementioned management principles and considered for study inclusion.

RESULTS

All high-level evidence studies that explored the various facets of SCS practice management were included for review.

LIMITATIONS

Both continued investigation into, and practice implementation of, the various facets of SCS management are necessary to optimize patient outcomes.

CONCLUSION

Implementation of and adherence to the evidenced-based recommendations delineated in this publication may help optimize efficacy outcomes and maintain safety profiles for persons treated with SCS interventions.

摘要

背景

慢性疼痛综合征的临床治疗极具挑战性,而阿片类药物治疗的效果越来越不理想。多项高质量、精心设计的研究表明,脊髓刺激(SCS)在治疗各种难治性慢性疼痛方面非常有效。SCS 的疗效和整体成功率高度依赖于对各种治疗方案的遵守和考虑。

目的

本手稿旨在综合提出脊髓刺激治疗管理的关键原则,包括:a)患者选择标准,b)SCS 对各种疾病的疗效,c)SCS 波形的讨论,d)试验和永久性植入的考虑,e)围手术期管理,以及 f)并发症和不良事件。

研究设计

循证叙述性综述。

方法

由两位作者分别对与上述管理原则相关的所有随机试验、荟萃分析和观察性研究进行了 PubMed、Medline、Cochrane 图书馆、先前的系统综述和参考文献列表的筛选,并考虑纳入研究。

结果

所有探索脊髓刺激治疗管理各个方面的高级别证据研究均被纳入综述。

局限性

对脊髓刺激治疗管理的各个方面进行持续的研究和实践实施是必要的,以优化患者的治疗效果。

结论

本研究中提出的循证建议的实施和遵守,可能有助于优化接受 SCS 干预的患者的疗效,并保持安全性。

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