Emerg Infect Dis. 2021 Feb;27(2):638-641. doi: 10.3201/eid2702.203824. Epub 2020 Nov 13.
We documented fetal death associated with intrauterine transmission of severe acute respiratory syndrome coronavirus 2. We found chronic histiocytic intervillositis, maternal and fetal vascular malperfusion, microglial hyperplasia, and lymphocytic infiltrate in muscle in the placenta and fetal tissue. Placenta and umbilical cord blood tested positive for the virus by PCR, confirming transplacental transmission.
我们记录了与严重急性呼吸综合征冠状病毒 2 宫内传播相关的胎儿死亡。我们在胎盘和胎儿组织中发现了慢性组织细胞绒毛膜炎、母胎血管灌注不良、小胶质细胞增生和淋巴细胞浸润。胎盘和脐带血通过 PCR 检测为病毒阳性,证实了胎盘传播。