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早孕期超声检查是否影响 13 周及以后人工流产的安全性?一项回顾性研究。

Does prior ultrasonography affect the safety of induced abortion at or after 13 weeks' gestation? A retrospective study.

机构信息

Ipas, Chapel Hill, NC, USA.

Ipas, Kathmandu, Nepal.

出版信息

Acta Obstet Gynecol Scand. 2021 Apr;100(4):736-742. doi: 10.1111/aogs.14040. Epub 2020 Dec 19.

Abstract

INTRODUCTION

We aimed to assess whether ultrasonography prior to dilation and evacuation or medical abortion ≥13 weeks was correlated with safety.

MATERIAL AND METHODS

We conducted a retrospective chart review of patients undergoing abortion ≥13 weeks at eight sites in Nepal from 2015 to 2019.

RESULTS

We included 2294 women undergoing abortion ≥13 weeks (no upper gestational age limit); 593 underwent dilation and evacuation and 1701 had a medical abortion. Demographics differed by procedure for parity (19% vs 33% nulliparous, dilation and evacuation, and medical abortion) and gestational age (90% vs 52% were 13-15 weeks, dilation and evacuation, and medical abortion). Ultrasonography was performed in 81% of cases overall. Complications were rare (<1% of dilations and evacuations, 1.4% of medical abortions). The most common adverse events with dilation and evacuation were hemorrhage and cervical laceration; three women required re-aspiration. Following medical abortion, 13.5% had retained products, 12.9% with prior ultrasound and 16.3% who had not had an ultrasound. Hemorrhage and severe side-effects occurred at similarly low rates regardless of whether ultrasonography was performed. In a logistic regression model where patient characteristics and case clustering within facilities were controlled for, we found a correlation between ultrasonography and complications when retained placenta was included in the model, but there was no correlation between ultrasonography and complications when retained placenta was excluded.

CONCLUSIONS

This study confirms low complication rates among women having an abortion ≥13 weeks' gestation in healthcare facilities. Settings without universal availability of ultrasound may still maintain low, comparable complication rates.

摘要

介绍

我们旨在评估在扩张和排空或药物流产≥13 周之前进行超声检查是否与安全性相关。

材料和方法

我们对 2015 年至 2019 年期间在尼泊尔的八个地点进行了≥13 周妊娠终止的患者进行了回顾性图表审查。

结果

我们纳入了 2294 名进行≥13 周妊娠终止的妇女(无最大妊娠年龄限制);593 名进行了扩张和排空,1701 名进行了药物流产。根据程序,人口统计学特征在产次上有所不同(19% vs 33% 初产妇,扩张和排空,药物流产)和孕龄上有所不同(90% vs 52% 为 13-15 周,扩张和排空,药物流产)。总体而言,81%的病例进行了超声检查。并发症很少见(扩张和排空<1%,药物流产 1.4%)。扩张和排空最常见的不良事件是出血和宫颈裂伤;三名妇女需要再次抽吸。药物流产后,13.5%有残留组织,12.9%有超声检查,16.3%没有超声检查。无论是否进行超声检查,出血和严重副作用的发生率都相似。在控制了患者特征和设施内病例聚类的逻辑回归模型中,我们发现超声检查与并发症之间存在相关性,当将胎盘残留纳入模型时,但当排除胎盘残留时,超声检查与并发症之间没有相关性。

结论

本研究证实了在医疗保健设施中进行≥13 周妊娠终止的妇女的并发症发生率较低。在没有普遍获得超声检查的情况下,仍可保持较低的、可比的并发症发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd97/8246849/6ae1fc9fb299/AOGS-100-736-g001.jpg

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