COVID-19 大流行期间的脑静脉窦血栓形成。
Cerebral Venous Sinus Thrombosis in the COVID-19 Pandemic.
机构信息
Department of Neurology (CM, RAP, SY, KI, JT), New York University Langone Medical Center, New York, New York; and Department of Neurology (AdH), University of Utah School of Medicine, Salt Lake City, Utah.
出版信息
J Neuroophthalmol. 2020 Dec;40(4):457-462. doi: 10.1097/WNO.0000000000001122. Epub 2020 Oct 28.
BACKGROUND
Recent studies have noted concern for increased thromboembolic events in the setting of Coronavirus Disease 2019 (COVID-19). Cerebral venous sinus thrombosis (CVST) is a form of thromboembolism that has been observed as a neuro-ophthalmologic complication of COVID-19.
METHODS
Review of the scientific literature.
RESULTS
In this article, we report an overview of CVST epidemiology, clinical presentation, diagnostics, disease pathophysiology, and management in the setting of COVID-19.
CONCLUSION
CVST is an uncommon thromboembolic event with variable phenotypes and multiple etiologies. Neurologic complications can be severe, including significant visual deficits and death. Current observations suggest that the risk of CVST may be profoundly impacted by this novel COVID-19 pandemic, thus prompting increased attention to disease presentation, pathogenesis, and management.
背景
最近的研究对 2019 年冠状病毒病（COVID-19）背景下血栓栓塞事件的增加表示关注。脑静脉窦血栓形成（CVST）是一种血栓栓塞，已被观察为 COVID-19 的神经眼科并发症。
方法
对科学文献的回顾。
结果
在本文中，我们报告了 COVID-19 背景下 CVST 的流行病学、临床表现、诊断、疾病病理生理学和治疗的概述。
结论
CVST 是一种罕见的血栓栓塞事件，具有不同的表型和多种病因。神经系统并发症可能很严重，包括严重的视力缺陷和死亡。目前的观察结果表明，这种新型 COVID-19 大流行可能会极大地影响 CVST 的风险，因此需要更加关注疾病的表现、发病机制和治疗。
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