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经皮冠状动脉介入治疗后出现的对比剂诱导短暂性神经症状:病例报告。

Contrast-Induced Transient Neurological Symptoms Following Percutaneous Coronary Intervention: A Case Report.

机构信息

Department of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

出版信息

Am J Case Rep. 2020 Nov 13;21:e926956. doi: 10.12659/AJCR.926956.

Abstract

BACKGROUND Transient neurological symptoms after a percutaneous coronary intervention (PCI) are not uncommon manifestations. In clinical practice, the development of these symptoms might be a warning sign for PCI-related ischemic or hemorrhagic stroke. However, there is a reported risk of contrast-induced neurological injury (CINI) after PCI, which results in a broad spectrum of transient and benign neurological symptoms. Advanced age, renal disease, diabetes, hypertension, and brain parenchymal lesions are risk factors for CINI. CASE REPORT A 78-year-old man with diabetes and impaired renal function developed left-sided hemiparesis and dysarthria within one hour of PCI. Non-contrast CT head showed hyperdense lesions in both frontal lobes, while the susceptibility-weighted sequence of magnetic resonance imaging (SWI-MRI) excludes hemorrhage. Hemodialysis had to be started for fast contrast clearance, and he had recovered completely within 24 hours. CONCLUSIONS This case demonstrates that CINI is an important differential diagnosis that cardiologists and neurologists must be familiar with, especially for high-risk patients. The prognosis is good; whether an appropriate contrast's dose or type for PCI or a need for early hemodialysis to avoid CINI in those patients is unclear.

摘要

背景

经皮冠状动脉介入治疗(PCI)后出现短暂性神经症状并不少见。在临床实践中,这些症状的出现可能是 PCI 相关缺血性或出血性卒中的警告信号。然而,PCI 后有报道称存在对比剂诱导的神经损伤(CINI)的风险,这会导致一系列短暂而良性的神经症状。高龄、肾脏疾病、糖尿病、高血压和脑实质病变是 CINI 的危险因素。

病例报告

一名 78 岁男性,患有糖尿病和肾功能受损,在 PCI 后 1 小时内出现左侧偏瘫和构音障碍。头部非对比 CT 显示双侧额叶高密度病灶,而磁共振成像(SWI-MRI)的磁敏感加权序列排除了出血。为了快速清除对比剂,不得不开始血液透析,他在 24 小时内完全恢复。

结论

本例表明,CINI 是心脏病专家和神经科医生必须熟悉的重要鉴别诊断,特别是对于高危患者。预后良好;对于这些患者,PCI 时使用合适的对比剂剂量或类型,或是否需要早期血液透析以避免 CINI,目前尚不清楚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd54/7672509/5debe2bde2b7/amjcaserep-21-e926956-g001.jpg

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