Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
Chem Commun (Camb). 2020 Dec 4;56(93):14601-14604. doi: 10.1039/d0cc06251k. Epub 2020 Nov 14.
A novel conjugate of a zinc(ii) phthalocyanine with three 2,4-dinitrobenzenesulfonate (DNBS) substituents, a bis(ferrocenylethenyl) boron dipyrromethene (BODIPY) and a pyrene connected respectively via an acid-sensitive ketal bridge and a singlet oxygen-cleavable thioketal linker has been designed and synthesised. It is responsive towards four stimuli, including glutathione (GSH), acid and light sources at a wavelength of >610 nm and 345 nm in a sequence-dependent manner, enabling it to function as a molecular keypad lock with the four inputs. This work represents a proof-of-concept study using specially designed molecules to perform complicated sequential logic operations.
一种新型锌（II）酞菁与三个 2,4-二硝基苯磺酸盐（DNBS）取代基、一个双（二茂铁乙烯基）硼二吡咯甲川（BODIPY）和一个芘通过分别通过酸敏感缩酮桥和单线态氧可裂解硫代缩酮连接子连接的轭合物已被设计和合成。它对四种刺激物有响应，包括谷胱甘肽（GSH）、酸和波长大于 610nm 和 345nm 的光源，以序列依赖性方式，使其能够作为具有四个输入的分子键盘锁工作。这项工作代表了使用专门设计的分子进行复杂顺序逻辑操作的概念验证研究。
