Malakoplakia of the bladder.

Malakoplakia is a disease which most commonly affects the bladder. It is probably more common than is realised because the appearance of the lesions is variable and the diagnosis can be difficult to make histologically. It should be considered in patients with recurring Escherichia coli infections and is also associated with immunosuppression and carcinoma. Three patients with malakoplakia of the bladder are reported: two had recurrent Esch. coli urinary tract infections and one had widespread urological malignancy. The pathogenesis is discussed and a simple treatment regime, which was rapidly successful in the patient who received it, is recommended.