Mycology Laboratory, New York State Department of Health Wadsworth Center, Albany, New York, NY, USA.
Department of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, NY, USA.
Trends Microbiol. 2020 Dec;28(12):954-956. doi: 10.1016/j.tim.2020.10.003. Epub 2020 Oct 21.
Candida auris, a multidrug-resistant fungal pathogen, is responsible for the recent global outbreaks in hospitalized and long-term care patients with significant mortality. A new study by Bruno et al. delineates innate host immune responses against C. auris and identifies critical roles for fungal mannans and mannoproteins.
耳念珠菌是一种多重耐药的真菌病原体,它是导致近期全球住院患者和长期护理患者中发生重大死亡的全球暴发的罪魁祸首。Bruno 等人的一项新研究描绘了针对耳念珠菌的固有宿主免疫反应,并确定了真菌甘露聚糖和甘露糖蛋白的关键作用。