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剧烈体育活动与1型糖尿病青少年更好的糖化血红蛋白水平及更低的低血糖恐惧评分相关:一项为期2年的随访研究。

Vigorous Physical Activity Is Associated With Better Glycated Hemoglobin and Lower Fear of Hypoglycemia Scores in Youth With Type 1 Diabetes: A 2-Year Follow-Up Study.

作者信息

Jabbour Georges

机构信息

Sport Science Program, College of Arts and Sciences, Qatar University, Doha, Qatar.

出版信息

Front Physiol. 2020 Oct 23;11:548417. doi: 10.3389/fphys.2020.548417. eCollection 2020.

Abstract

To correlate glycated hemoglobin (HbA1c) and fear of hypoglycemia scores with physical activity (PA) levels in children and adolescents with type 1 diabetes (T1D) over a period of 2 years. Twenty-eight children and 33 adolescents with T1D have been assessed for their PA profile. Personal and medical data for the patients were collected at baseline (visit 0: V0), 1 year later (V1), and 2 years later (V2). At baseline, children with T1D engaged in less moderate to vigorous PA (MVPA) ( < 0.01) per day than adolescents. These results did not differ across visits. On the contrary, adolescents spent fewer time in vigorous physical activity (VPA) ( < 0.01) than children did ( < 0.01). Fear of hypoglycemia scores correlated significantly with VPA levels (β = -0.41, = 0.03; β = -0.44, = 0.06; β = -0.61, = 0.001). For HbA1c (%), significant correlations were reported with VPA levels (β = -0.54, = 0.02; β = -0.47, = 0.03; β = -0.62, = 0.01) across visits. Body mass index percentile correlated with total screen time (β = 0.28, = 0.02; β = 0.29, = 0.01; β = 0.31, = 0.04) and overall PA levels (β = -0.52, = 0.02; β = -0.42, = 0.03; β = -0.42, = 0.01). Performing more vigorous PA a day is associated with better HbA1c with lower perceived fear of hypoglycemia among youth with T1D. Therefore, dedicating more time in VPA may be an appropriate advice for patients with T1D.

摘要

在2年的时间里,将1型糖尿病(T1D)儿童和青少年的糖化血红蛋白(HbA1c)及低血糖恐惧评分与身体活动(PA)水平进行关联分析。对28名患有T1D的儿童和33名患有T1D的青少年的PA情况进行了评估。在基线(访视0:V0)、1年后(V1)和2年后(V2)收集了患者的个人和医疗数据。在基线时,患有T1D的儿童每天进行的中度至剧烈PA(MVPA)(<0.01)比青少年少。这些结果在各次访视中没有差异。相反,青少年进行剧烈身体活动(VPA)的时间(<0.01)比儿童少(<0.01)。低血糖恐惧评分与VPA水平显著相关(β = -0.41,P = 0.03;β = -0.44,P = 0.06;β = -0.61,P = 0.001)。对于HbA1c(%),在各次访视中均报告与VPA水平存在显著相关性(β = -0.54,P = 0.02;β = -0.47,P = 0.03;β = -0.62,P = 0.01)。体重指数百分位数与总屏幕时间(β = 0.28,P = 0.02;β = 0.29,P = 0.01;β = 0.31,P = 0.04)及总体PA水平(β = -0.52,P = 0.02;β = -0.42,P = 0.03;β = -0.42,P = 0.01)相关。每天进行更多的剧烈PA与T1D青少年更好的HbA1c及更低的低血糖感知恐惧相关。因此,建议T1D患者在VPA上投入更多时间可能是合适的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f019/7645069/60062a4abfcf/fphys-11-548417-g001.jpg

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