头皮鳞状细胞癌复发并侵犯脑部的治疗：一例报告及文献综述
Management of a recurrence of a squamous cell carcinoma of the scalp with extension to the brain: A case report and literature review.
作者信息
Chabaane Mohamed, Ayadi Khalil, Rkhami Mouna, Drissi Cyrine, Houimli Sarra, Bahri Kamel, Zammel Ihsen, Badri Mohamed
机构信息
Department of Neurosurgery, Trauma and Burns Center Ben Arous, Ben Arous, Tunisia.
Department of Neuroradiology, National Institute of Neurology, Tunis, Tunisia.
出版信息
Surg Neurol Int. 2020 Oct 21;11:347. doi: 10.25259/SNI_356_2020. eCollection 2020.
BACKGROUND
Squamous cell carcinoma (SCC) is the most common form of nonmelanoma skin cancer after basal cell carcinoma. Simple excision can be the treatment at early stages of diagnosis. However, at late stages, treatment is more complex due to extension to the skull and the dura. In extremely rare cases, it can invade the brain making it a challenging situation for treatment.
CASE DESCRIPTION
We present the case of a 54-year-old man with a history of cutaneous SCC who presented an invasive left frontal recurrence with brain invasion 19 years after initial surgery. The patient underwent surgery which consisted in tumor removal and bone and skin reconstruction. Immediate and late outcomes were favorable.
CONCLUSION
Multidisciplinary treatment for SCC diagnosed in advanced stages is the best way to obtain encouraging results. Although significant advancements have been made, further study is needed for cases with advanced disease.
背景
鳞状细胞癌（SCC）是继基底细胞癌之后最常见的非黑素瘤皮肤癌形式。在诊断早期，单纯切除即可作为治疗方法。然而，在晚期，由于肿瘤扩展至颅骨和硬脑膜，治疗更为复杂。在极其罕见的情况下，它可侵入大脑，使治疗成为具有挑战性的情况。
病例描述
我们报告一例54岁男性，有皮肤SCC病史，在初次手术后19年出现左额叶侵袭性复发并侵犯大脑。患者接受了手术，包括肿瘤切除以及骨和皮肤重建。近期和远期结果均良好。
结论
对晚期诊断出的SCC进行多学科治疗是获得令人鼓舞结果的最佳方法。尽管已取得重大进展，但对于晚期疾病病例仍需要进一步研究。
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