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风湿病学家在抗击新冠疫情中的角色:来自一线的见解与未来挑战

The Rheumatologist's Role in the Battle Against COVID-19: Insights from the Front Line and Challenges for the Future.

作者信息

Koutsianas Christos, Chatzidionysiou Katerina

机构信息

Department of Rheumatology, The Dudley Group NHS Foundation Trust, Dudley, West Midlands, United Kingdom.

Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institute, Stockholm, Sweden.

出版信息

Mediterr J Rheumatol. 2020 Sep 21;31(Suppl 2):247-252. doi: 10.31138/mjr.31.3.247. eCollection 2020 Sep.

Abstract

As the worldwide burden of COVID-19 increases exponentially, healthcare systems are plagued by unprecedented pressure. In this setting, many rheumatologists across the globe have been recruited to support the front line, facing several unexpected challenges, but also providing valuable skills in combating COVID-19. At the same time, the rheumatic disease patient population may be especially vulnerable to such a rapidly contagious infectious disease and thus needs care and support that has to be provided quickly and efficiently. Clear advice on viral spread mitigation, precise guidelines on immunosuppressive treatment use and alternative methods of providing care, such as telemedicine, are a few of the rheumatologists' new challenges in caring for their patients in the COVID-19 era. Finally, among other specialties, rheumatologists hold a unique place in the fight against the hyper-inflammatory state caused by severe SARS-CoV-2 infection, leading to increased morbidity and mortality. Given their vast experience in the use of biologic and targeted therapies, rheumatologists should lead the way in developing reliable scientific evidence for the optimal treatment of severe COVID-19.

摘要

随着新冠疫情在全球的负担呈指数级增长,医疗系统正面临前所未有的压力。在这种情况下,全球许多风湿病学家被招募来支援前线,他们面临着一些意想不到的挑战,但也在抗击新冠疫情中发挥了宝贵作用。与此同时,风湿病患者群体可能特别容易受到这种快速传播的传染病的影响,因此需要迅速而有效地提供护理和支持。关于减轻病毒传播的明确建议、免疫抑制治疗使用的精确指南以及提供护理的替代方法,如远程医疗,是风湿病学家在新冠疫情时代照顾患者时面临的一些新挑战。最后,在其他专科中,风湿病学家在对抗由严重SARS-CoV-2感染引起的过度炎症状态方面占据独特地位,这种状态会导致发病率和死亡率上升。鉴于他们在使用生物制剂和靶向治疗方面的丰富经验,风湿病学家应率先为重症新冠疫情的最佳治疗提供可靠的科学依据。

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