Epidemiology and Biostatistics Institute, School of Public Health, Tianjin Medical University, Tianjin, China.
Tianjin Shenlan Community-Based Organization, Tianjin, China.
HIV Med. 2021 Mar;22(3):185-193. doi: 10.1111/hiv.12990. Epub 2020 Nov 16.
Despite being a key population in whom to initiate pre-exposure prophylaxis (PrEP), the awareness of and willingness to use PrEP are still unclear in Chinese young men who have sex with men (YMSM). We report factors associated with PrEP awareness and willingness in the population.
From 1 August to 31 December 2018, 495 participants aged 15-24 years were included in a cross-sectional study about awareness of and willingness to use PrEP among YMSM. Logistic regression models were used to identify factors associated with two outcomes: awareness of PrEP; and willingness to use PrEP.
Among 495 eligible participants, 129 participants (26.1%) knew about PrEP. PrEP awareness among YMSM was associated with higher education level [adjusted odds ratio (aOR) = 1.812, 95% CI: 1.113-2.951] and previous HIV testing (aOR = 3.507, 95% CI: 1.261-9.752). YMSM with shorter local residence time (aOR = 0.317, 95% CI: 0.101-0.992) and internet-based partner-seeking (aOR = 0.171, 95% CI: 0.096-0.305) were less likely to be aware of PrEP. In those with previous knowledge of PrEP, 36 (27.9%) conveyed their willingness to use it. PrEP willingness was associated with internet-based partner-seeking (aOR = 9.593, 95% CI: 1.965-46.844). The main barriers influencing those who knew about PrEP but refused to use it were the high price of PrEP (69.9%), the need to use condoms consistently (52.7%), and concerns about side effects (39.8%) and effectiveness of prevention (22.6%).
Chinese YMSM have low awareness of and willingness to use PrEP. Adequate PrEP promotions should be implemented, especially on the Internet and dating software.
尽管男男性行为者（MSM）是开始暴露前预防（PrEP）的关键人群，但中国年轻 MSM 对 PrEP 的认知和使用意愿仍不清楚。我们报告了与该人群 PrEP 认知和使用意愿相关的因素。
2018 年 8 月 1 日至 12 月 31 日，我们对 495 名年龄在 15-24 岁的男男性行为者进行了一项横断面研究，了解他们对 PrEP 的认知和使用意愿。使用逻辑回归模型确定了与两个结果相关的因素：对 PrEP 的认知；以及使用 PrEP 的意愿。
在 495 名符合条件的参与者中，有 129 名（26.1%）了解 PrEP。MSM 对 PrEP 的认知与较高的受教育程度相关（调整后的优势比[aOR] = 1.812，95%置信区间[CI]：1.113-2.951）和既往 HIV 检测（aOR = 3.507，95% CI：1.261-9.752）。当地居住时间较短（aOR = 0.317，95% CI：0.101-0.992）和基于互联网的伴侣寻找（aOR = 0.171，95% CI：0.096-0.305）的 MSM 不太可能了解 PrEP。在那些之前了解 PrEP 的人群中，有 36 人（27.9%）表示愿意使用 PrEP。PrEP 意愿与基于互联网的伴侣寻找相关（aOR = 9.593，95% CI：1.965-46.844）。影响那些了解 PrEP 但拒绝使用的主要障碍是 PrEP 价格高（69.9%）、需要持续使用避孕套（52.7%）、以及对副作用（39.8%）和预防效果（22.6%）的担忧。
中国年轻 MSM 对 PrEP 的认知和使用意愿较低。应实施适当的 PrEP 推广措施，特别是在互联网和约会软件上。
