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癌症幸存者的医用大麻消费初步评估。

Preliminary assessment of medical cannabis consumption by cancer survivors.

机构信息

Regional Drug and Alcohol Research Center, Ben Gurion University of the Negev, RADAR Center, Building #17, 84105 Beer Sheva Israel.

Supportive Care Unit, The Cancer Center at Sheba Medical Center, Israel.

出版信息

Complement Ther Med. 2021 Jan;56:102592. doi: 10.1016/j.ctim.2020.102592. Epub 2020 Oct 9.

Abstract

OBJECTIVES

To assess the motivation of cancer survivors to consume medical cannabis and to assess the patterns of use, perceived efficacy, as well as side and adverse effects.

METHODS

Cross-sectional survey among 190 Israeli cancer survivors who were licensed to use medical cannabis in a single institution. In addition to demographic information, the questionnaire examined patterns of use (including dosage, type of cannabis and way of administration), motivation for medical cannabis consumption, perceived efficacy, adverse and side effects, motivation for ceasing cannabis consumption, and tobacco smoking.

RESULTS

The mean monthly dosage of cannabis consumed was 42.4 grams; 95.8% of respondents reported not consuming cannabis regularly before being diagnosed with cancer; the most common way of administration was smoking, and most of the participants reported taking cannabis throughout the day. The most common symptoms for which participants took medical cannabis were pain (n = 169, 88.9%), sleeping disorder (n = 144, 75.8%) and anxiety (n = 79, 41.6%). Twenty patients (10.5%) reported on mild side (or adverse) effects.

CONCLUSIONS

This study indicates that cancer survivors may indeed consume cannabis for symptom relief, and not merely for recreational purposes. Although our findings point to perceived safety and efficacy of medical cannabis for cancer survivors, more research is needed to study the adequate role that cannabis may have for treating symptoms associated with cancer survivorship.

摘要

目的

评估癌症幸存者使用医用大麻的动机,并评估使用模式、感知疗效以及副作用和不良反应。

方法

在一家机构中,对 190 名获得医用大麻使用许可证的以色列癌症幸存者进行横断面调查。除了人口统计学信息外,问卷还调查了使用模式(包括剂量、大麻类型和给药方式)、使用医用大麻的动机、感知疗效、副作用和不良反应、停止使用大麻的动机以及吸烟情况。

结果

大麻的月平均剂量为 42.4 克;95.8%的受访者报告在被诊断出患有癌症之前没有定期吸食大麻;最常见的给药方式是吸烟,大多数参与者报告全天吸食大麻。参与者因以下症状而使用医用大麻:疼痛(n = 169,88.9%)、睡眠障碍(n = 144,75.8%)和焦虑(n = 79,41.6%)。20 名患者(10.5%)报告有轻度副作用(或不良反应)。

结论

本研究表明,癌症幸存者确实可能因缓解症状而使用大麻,而不仅仅是为了娱乐目的。尽管我们的研究结果表明医用大麻对癌症幸存者来说是安全且有效的,但仍需要更多的研究来探讨大麻在治疗与癌症生存相关的症状方面可能发挥的适当作用。

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