Petersen F B, Buckner C D
Fred Hutchinson Cancer Research Center, Seattle, Washington 98104.
Hematol Oncol. 1987 Oct-Dec;5(4):233-43. doi: 10.1002/hon.2900050402.
The current status of autologous and allogeneic marrow transplantation for acute leukemias and malignant lymphoma is reviewed and compared to the current status of conventional chemotherapy. Based on the reviewed literature, it is concluded that marrow transplantation and conventional chemoradiotherapy are not mutually exclusive and that for most young patients with acute hematological malignancies the question is not if, but rather when to intervene with a marrow transplant treatment. Thus marrow transplantation and conventional chemoradiotherapy can work as complimentary units in the complex therapeutic approach needed to cure most patients with hematological malignancies.
本文回顾了急性白血病和恶性淋巴瘤自体及异体骨髓移植的现状，并与传统化疗的现状进行了比较。基于所回顾的文献，得出的结论是骨髓移植和传统放化疗并非相互排斥，对于大多数患有急性血液系统恶性肿瘤的年轻患者来说，问题不在于是否进行骨髓移植治疗，而在于何时进行干预。因此，骨髓移植和传统放化疗可以作为互补单元，共同用于治愈大多数血液系统恶性肿瘤患者所需的复杂治疗方法中。
