Anokwute Akudo U, Bakare Olusegun, Ogbuji Chukwunonye O, Arinze Nkechi C
Internal Medicine, Brookdale University Hospital Medical Center, Brooklyn, USA.
Internal Medicine, Thomas Jefferson University, Philadelphia, USA.
Cureus. 2020 Oct 14;12(10):e10946. doi: 10.7759/cureus.10946.
Immunoglobulin A (IgA) vasculitis (IgAV), also known as Henoch-Schonlein purpura, is an IgA-mediated leukocytoclastic vasculitis predominantly affecting the gastrointestinal tract, kidneys, and skin. IgAV appears to be more common in children and is relatively rare in the adult population. We describe a case of a 72-year-old man who presented with bilateral lower extremity swelling, nausea, vomiting, abdominal pain, and weight loss, in which a diagnosis of IgAVs was established with a skin biopsy. This case highlights a rare and unusual clinical presentation of IgAV in an older patient and the need for prompt diagnosis and treatment.
免疫球蛋白A（IgA）血管炎（IgAV），也称为过敏性紫癜，是一种由IgA介导的白细胞破碎性血管炎，主要影响胃肠道、肾脏和皮肤。IgAV在儿童中似乎更为常见，在成人中相对罕见。我们描述了一例72岁男性患者，他出现双侧下肢肿胀、恶心、呕吐、腹痛和体重减轻，通过皮肤活检确诊为IgAV。该病例突出了IgAV在老年患者中罕见且不寻常的临床表现，以及及时诊断和治疗的必要性。
