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纤维蛋白原/白蛋白比值与稳定型冠状动脉疾病患者冠状动脉侧支循环的关系。

Association of fibrinogen/albumin ratio and coronary collateral circulation in stable coronary artery disease patients.

机构信息

Department of Geriatric Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, PR China.

Department of Cardiology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, PR China.

出版信息

Biomark Med. 2020 Nov;14(16):1513-1520. doi: 10.2217/bmm-2020-0333. Epub 2020 Nov 17.

Abstract

To investigate whether fibrinogen/albumin ratio (FAR) has an association with the coronary collateral circulation (CCC) in patients with stable coronary artery disease. A total of 391 patients with stable coronary artery disease who underwent coronary angiography were included. The patients were divided into two groups according to the Rentrop score. The poorly developed CCC group had a significantly higher FAR level compared with the well-developed CCC group (p < 0.001). In the multivariate analysis, the FAR (odds ratio: 1.700; 95% CI: 1.420-2.036; p < 0.001) was an independent predictor of poorly developed CCC. FAR can be used as one of the independent predictors of CCC formation.

摘要

为了探讨纤维蛋白原/白蛋白比值(FAR)与稳定型冠状动脉疾病患者的冠状动脉侧支循环(CCC)是否有关,纳入了 391 例接受冠状动脉造影的稳定型冠状动脉疾病患者。根据Rentrop 评分将患者分为两组。CCC 发育不良组的 FAR 水平明显高于 CCC 发育良好组(p<0.001)。在多变量分析中,FAR(比值比:1.700;95%可信区间:1.420-2.036;p<0.001)是 CCC 发育不良的独立预测因子。FAR 可作为 CCC 形成的独立预测因子之一。

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