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在复杂的冠状动脉血管成形术中联合使用旋转和准分子激光冠状动脉斑块切除术(RASER)——来自英国心血管介入学会数据库的病例分析(2006-2016 年)。

Combined use of rotational and excimer lASER coronary atherectomy (RASER) during complex coronary angioplasty-An analysis of cases (2006-2016) from the British Cardiovascular Intervention Society database.

机构信息

Department of Cardiology, University Hospital of Wales, Cardiff, UK.

Systems Immunity University Research Institute, Cardiff University, Cardiff, UK.

出版信息

Catheter Cardiovasc Interv. 2021 Jun 1;97(7):E911-E918. doi: 10.1002/ccd.29377. Epub 2020 Nov 17.

DOI:10.1002/ccd.29377
PMID:33201601
Abstract

INTRODUCTION

Combining rotational (RA) and excimer laser coronary atherectomy (ELCA)-RASER atherectomy-is technique utilized in the percutaneous management of calcific coronary disease. The evidence base examining its safety and utility is sparse and limited to small case-series. This study examines the patterns and outcomes of RASER atherectomy use in the largest cohort to date.

METHODS

Using the British Cardiac Intervention Society database, data were analyzed on all PCI procedures in the UK between 2006 and 2016. Descriptive statistics and multivariate logistic regressions were used to examine baseline, procedural, and outcome associations with RASER.

RESULTS

We identified 153 (0.02%) RASER atherectomy cases out of 686,358 PCI procedures. Baseline covariates associated with RASER use were age, BMI, diabetes, stable coronary disease, and previous CABG. Procedural co-variates associated with RASER were CTO-PCI, the use of more/longer stents, intravascular imaging, cutting balloons, and microcatheters. Adjusted rates of in-hospital major adverse cardiac/cerebrovascular events (MACCE) were not significantly different with RASER. However, there were higher odds of arterial complications (OR 3.23, 95% CI: 1.58-6.61), slow flow (OR 3.50, 95% CI: 1.29-9.55), and shock induction (OR 9.66, 95% CI: 3.44-27.06).

CONCLUSIONS

RASER atherectomy use in complex PCI is associated with higher risk baseline and procedural characteristics. Although increased rates of shock induction, slow flow, and arterial complications were observed, RASER does not increase the likelihood of in-hospital MACCE, major bleeding, or death.

摘要

简介

旋转(RA)和准分子激光冠状动脉旋磨术(ELCA)-RASTER 旋磨术的结合是一种用于经皮治疗钙化性冠状动脉疾病的技术。检查其安全性和实用性的证据基础很少且仅限于小病例系列。本研究检查了迄今为止最大队列中 RASTER 旋磨术使用的模式和结果。

方法

使用英国心脏介入学会数据库,分析了 2006 年至 2016 年期间英国所有 PCI 手术的数据。使用描述性统计和多变量逻辑回归检查 RASER 的基线、程序和结果相关性。

结果

我们在 686,358 例 PCI 手术中发现了 153 例(0.02%)RASTER 旋磨术病例。与 RASER 使用相关的基线协变量为年龄、BMI、糖尿病、稳定性冠心病和先前的 CABG。与 RASER 相关的程序协变量为 CTO-PCI、使用更多/更长的支架、血管内成像、切割球囊和微导管。使用 RASER 的住院期间主要不良心脏/脑血管事件(MACCE)的调整后发生率没有显著差异。然而,动脉并发症(OR 3.23,95%CI:1.58-6.61)、慢血流(OR 3.50,95%CI:1.29-9.55)和休克诱导(OR 9.66,95%CI:3.44-27.06)的可能性更高。

结论

RASTER 旋磨术在复杂 PCI 中的使用与更高的基线和程序特征风险相关。尽管观察到休克诱导、慢血流和动脉并发症的发生率增加,但 RASER 并不会增加住院 MACCE、大出血或死亡的可能性。

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