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冠状动脉影像学对旋磨术介入治疗结果的影响:英国心血管介入学会数据库中 8417 例旋磨术病例分析。

The Impact of Intracoronary Imaging on PCI Outcomes in Cases Utilising Rotational Atherectomy: An Analysis of 8,417 Rotational Atherectomy Cases from the British Cardiovascular Intervention Society Database.

机构信息

Department of Cardiology, University Hospital of Wales, Cardiff, UK.

Systems Immunity University Research Institute, Cardiff University, Cardiff, UK.

出版信息

J Interv Cardiol. 2022 Mar 15;2022:5879187. doi: 10.1155/2022/5879187. eCollection 2022.

Abstract

INTRODUCTION

There is increasing evidence supporting the use of intracoronary imaging to optimize the outcomes of percutaneous coronary intervention (PCI). However, there are no studies examining the impact of imaging on PCI outcomes in cases utilising rotational atherectomy (RA-PCI). Our study examines the determinants and outcomes of using intracoronary imaging in RA-PCI cases including 12-month mortality.

METHODS

Using the British Cardiac Intervention Society database, data were analysed on all RA-PCI procedures in the UK between 2007 and 2014. Descriptive statistics and multivariate logistic regressions were used to examine baseline, procedural, and outcome associations with intravascular imaging.

RESULTS

Intracoronary imaging was used in 1,279 out of 8,417 RA-PCI cases (15.2%). Baseline covariates associated with significantly more imaging use were number of stents used, smoking history, previous CABG, pressure wire use, proximal LAD disease, laser use, glycoprotein inhibitor use, cutting balloons, number of restenosis attempted, off-site surgery, and unprotected left main stem (uLMS) PCI. Adjusted rates of in-hospital major adverse cardiac/cerebrovascular events (IH-MACCE), its individual components (death, peri-procedural MI, stroke, and major bleed), or 12-month mortality were not significantly altered by the use of imaging in RA-PCI. However, subgroup analysis demonstrated a signal towards reduction in 12-month mortality in uLMS RA-PCI cases utilising intracoronary imaging (OR 0.67, 95% CI 0.44-1.03).

CONCLUSIONS

Intracoronary imaging use during RA-PCI is associated with higher risk of baseline and procedural characteristics. There were no differences observed in IH-MACCE or 12-month mortality with intracoronary imaging in RA-PCI.

摘要

简介

越来越多的证据支持使用冠状动脉内影像学来优化经皮冠状动脉介入治疗(PCI)的结果。然而,目前尚无研究探讨影像学在利用旋磨术(RA-PCI)的 PCI 中的影响。我们的研究考察了在 RA-PCI 病例中使用冠状动脉内影像学的决定因素和结果,包括 12 个月的死亡率。

方法

利用英国心脏介入学会数据库,分析了 2007 年至 2014 年期间英国所有 RA-PCI 手术的数据。使用描述性统计和多变量逻辑回归分析检查了基线、手术过程和结果与血管内影像学的关联。

结果

在 8417 例 RA-PCI 病例中,有 1279 例(15.2%)使用了冠状动脉内影像学。与更多使用影像学相关的基线协变量包括使用支架的数量、吸烟史、既往 CABG、压力导丝使用、近端左前降支疾病、激光使用、糖蛋白抑制剂使用、切割球囊、尝试再狭窄的数量、非现场手术和无保护的左主干(uLMS)PCI。RA-PCI 中使用影像学并未显著改变住院期间主要不良心脏/脑血管事件(IH-MACCE)的发生率及其各个组成部分(死亡、围手术期 MI、卒中和大出血),或 12 个月的死亡率。然而,亚组分析显示,在 uLMS RA-PCI 病例中,使用冠状动脉内影像学与 12 个月死亡率降低相关(OR 0.67,95%CI 0.44-1.03)。

结论

RA-PCI 中使用冠状动脉内影像学与更高的基线和手术特征风险相关。在 RA-PCI 中使用冠状动脉内影像学并未观察到 IH-MACCE 或 12 个月死亡率的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd02/8941577/35b215227235/JITC2022-5879187.001.jpg

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