Helwig Angeniet, Smulders Yvo
MUMC+, Maastricht.
Contact: Angeniet Helwig (
Ned Tijdschr Geneeskd. 2020 Sep 24;164:D4762.
Half of all Dutch people take nutritional supplements, vitamins amongst others. The fact that vitamins can be toxic when taken in overdose is not common knowledge. There is no evidence that taking vitamin supplements without medical indication improves the health of people with a varied diet. Many are seduced by health claims to use vitamin supplements, unaware of the fact that the evidence for effectiveness is lacking, let alone of the risks of overdosing. In this article, we describe the known toxic symptoms of each vitamin. Furthermore, the toxic doses were indexed against the available dosage, both through regular pharmacies and online. The doses reported to have toxic effects have not always been properly studied. Consequently, toxic doses may be higher or lower than the doses mentioned in this article. The vitamins for which no toxic effects have been described are not automatically safe in every dosis, considering the lack of systematic research into the potential toxicity of vitamins.
一半的荷兰人服用营养补充剂,其中包括维生素。维生素过量服用会有毒性这一事实并非广为人知。没有证据表明在没有医学指征的情况下服用维生素补充剂能改善饮食多样的人的健康状况。许多人被健康宣称所诱惑而使用维生素补充剂,却没有意识到缺乏有效性证据,更不用说过量服用的风险了。在本文中,我们描述了每种维生素已知的毒性症状。此外,还将有毒剂量与通过正规药店和在线渠道可得的剂量进行了对比。报告显示有有毒作用的剂量并非总是经过充分研究的。因此,有毒剂量可能高于或低于本文提及的剂量。鉴于缺乏对维生素潜在毒性的系统研究,未描述有毒作用的维生素并不意味着在任何剂量下都是安全的。