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心力衰竭患者如何进行日常活动:一种先天的节能策略。

How Patients With Heart Failure Perform Daily Life Activities: An Innate Energy-Saving Strategy.

机构信息

Centro Cardiologico Monzino, IRCCS, Milano, Italy (M.M., E.S., A.B., P.G., F.D.M., C.V., G.B., P.A.).

Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milano, Italy (M.M., C.V., P.A.).

出版信息

Circ Heart Fail. 2020 Nov;13(11):e007503. doi: 10.1161/CIRCHEARTFAILURE.120.007503. Epub 2020 Nov 17.

Abstract

BACKGROUND

Cardiopulmonary exercise test and 6-minute walking test are frequently used tools to evaluate physical performance in heart failure (HF), but they do neither represent activities of daily living (ADLs) nor fully reproduce patients' symptoms. We assessed differences in task oxygen uptake, both as absolute value and as percentage of peak oxygen consumption (peakVO), ventilation efficiency (VE/VCO ratio), and dyspnea intensity (Borg scale) in HF and healthy subjects during standard ADLs and other common physical actions.

METHODS

Healthy and HF subjects (ejection fraction <45%, stable conditions) underwent cardiopulmonary exercise test. All of them, carrying a wearable metabolic cart, performed a 6-minute walking test, two 4-minute treadmill exercises (at 2 and 3 km/h), and ADLs: ADL1 (getting dressed), ADL2 (folding 8 towels), ADL3 (putting away 6 bottles), ADL4 (making a bed), ADL5 (sweeping the floor for 4 minutes), ADL6 (climbing 1 flight of stairs carrying a load).

RESULTS

Sixty patients with HF (age 65.2±12.1 years; ejection fraction 30.4±6.7%, peakVO 14.2±4.0 mL/[min·kg]) and 40 healthy volunteers (58.9±8.2 years, peakVO 28.1±7.4 mL/[min·kg]) were enrolled. For each exercise, patients showed higher VE/VCO ratio, percentage of peakVO, and Borg scale value than controls, while absolute values of task oxygen uptake and exercise duration were lower and higher, respectively, in all activities, except for treadmill (fixed execution time and intensity). Differently from Borg Scale data, metabolic values and exercise time length changed in parallel with HF severity, except for ADL duration in very short (ADL3) and composite (ADL1) activities. Borg scale values correlated with percentage of peakVO.

CONCLUSIONS

During ADLs, patients self-regulated activities in parallel with HF severity by decreasing intensity (VO) and prolonging the effort.

摘要

背景

心肺运动试验和 6 分钟步行试验常用于评估心力衰竭(HF)患者的体力表现,但它们既不能代表日常生活活动(ADL),也不能完全再现患者的症状。我们评估了 HF 患者和健康受试者在进行标准 ADL 和其他常见身体活动时,任务摄氧量的绝对值和峰值摄氧量(peakVO)的百分比、通气效率(VE/VCO 比值)和呼吸困难强度(Borg 量表)的差异。

方法

健康受试者和 HF 患者(射血分数<45%,病情稳定)进行心肺运动试验。所有受试者均携带可穿戴代谢箱,进行 6 分钟步行试验、2 次 4 分钟跑步机运动(速度分别为 2 和 3km/h)以及 ADL:ADL1(穿衣服)、ADL2(折叠 8 条毛巾)、ADL3(放 6 个瓶子)、ADL4(铺床)、ADL5(扫地 4 分钟)、ADL6(负重爬 1 层楼梯)。

结果

共纳入 60 例 HF 患者(年龄 65.2±12.1 岁;射血分数 30.4±6.7%,peakVO 14.2±4.0mL/[min·kg])和 40 名健康志愿者(58.9±8.2 岁,peakVO 28.1±7.4mL/[min·kg])。对于每项运动,患者的 VE/VCO 比值、peakVO 百分比和 Borg 量表值均高于对照组,而任务摄氧量的绝对值和运动时间则分别在所有活动中较低和较高,除了跑步机(固定执行时间和强度)。与 Borg 量表数据不同,代谢值和运动时间长度与 HF 严重程度呈平行变化,除了非常短的(ADL3)和综合的(ADL1)活动外,ADL 持续时间也呈平行变化。Borg 量表值与 peakVO 百分比相关。

结论

在 ADL 中,患者通过降低强度(VO)和延长努力来自我调节活动,以适应 HF 的严重程度。

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