Punjani Nahid, Kang Caroline, Lamb Dolores J
James Buchanan Brady Foundation Institute of Urology, Weill Cornell Medical College, New York, NY, USA.
Englander Institute for Precision Medicine, Weill Cornell Medical College, New York, NY, USA.
Turk J Urol. 2020 Oct 30. doi: 10.5152/tud.2020.20463.
Male infertility is a common problem. There is growing evidence that infertile men may harbor significant illness and disease. Many of the genetic causes of male fertility have implications on other systemic illnesses. This review aims to discuss various genetic conditions and gene mutations and alterations associated with male infertility and evidence for associated systemic conditions. These findings highlight the importance of a thorough workup in men presenting for a fertility assessment.
男性不育是一个常见问题。越来越多的证据表明,不育男性可能患有严重疾病。男性生育能力的许多遗传原因与其他全身性疾病有关。本综述旨在讨论与男性不育相关的各种遗传状况、基因突变和改变,以及相关全身性疾病的证据。这些发现凸显了对前来进行生育能力评估的男性进行全面检查的重要性。