Zalev Jason, Kolios Michael C
IEEE Trans Ultrason Ferroelectr Freq Control. 2021 May;68(5):1885-1906. doi: 10.1109/TUFFC.2020.3038622. Epub 2021 Apr 26.
Simulation involves predicting the responses of a physical system. In this article, we simulate opto-acoustic signals generated in a 3-D volume due to the absorption of an optical pulse. A separable computational model is developed, which splits processing into two steps, permitting an order-of-magnitude improvement in computational efficiency over a nonseparable model. The simulated signals represent acoustic waves, measured by a probe with a linear transducer array, in a rotated and translated coordinate frame. Light is delivered by an optical source that moves with the probe's frame. Spatiotemporal impulse response for rectangular-element transducer geometry is derived using Green's function solution to the acoustic wave equation. The approach permits fast and accurate simulation for a probe with an arbitrary trajectory, which is useful for modeling freehand acquisitions. For a 3-D volume of n voxels, computation is accelerated by a factor of n . This may potentially have application in opto-acoustic imaging, where clinicians visualize structural and functional features of biological tissue for assessment of cancer and other diseases.
模拟涉及预测物理系统的响应。在本文中，我们模拟了由于光脉冲吸收而在三维体积中产生的光声信号。我们开发了一种可分离的计算模型，该模型将处理过程分为两个步骤，与不可分离模型相比，计算效率提高了一个数量级。模拟信号表示在旋转和平移坐标系中由带有线性换能器阵列的探头测量的声波。光是由与探头框架一起移动的光源传输的。使用声波方程的格林函数解推导出矩形元件换能器几何形状的时空脉冲响应。该方法允许对具有任意轨迹的探头进行快速准确的模拟，这对于徒手采集建模很有用。对于具有n个体素的三维体积，计算速度加快了n倍。这可能在光声成像中有应用，临床医生可以在光声成像中可视化生物组织的结构和功能特征，以评估癌症和其他疾病。
