Department of Medicine and Aged Care, @AgeMelbourne, The Royal Melbourne Hospital, The University of Melbourne, Melbourne, VIC, Australia.
Department of Human Movement Sciences, @AgeAmsterdam, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, the Netherlands.
Int J Clin Pract. 2021 Apr;75(4):e13838. doi: 10.1111/ijcp.13838. Epub 2020 Dec 14.
Older adults often suffer from multimorbidity, which results in hospitalisations. These are often associated with poor health outcomes such as functional dependence and mortality. The aim of this review was to summarise the current literature on the capacities of morbidity measures in predicting activities of daily living (ADL) and instrumental activities of daily living (IADL) amongst inpatients.
A systematic literature search was performed using four databases: Medline, Cochrane, Embase, and Cinahl Central from inception to 6th March 2019. Keywords included comorbidity, multimorbidity, ADL, and iADL, along with specific morbidity measures. Articles reporting on morbidity measures predicting ADL and IADL decline amongst inpatients aged 65 years or above were included.
Out of 7334 unique articles, 12 articles were included reporting on 7826 inpatients (mean age 77.6 years, 52.7% females). Out of five morbidity measures, the Charlson Comorbidity Index was most often reported. Overall, morbidity measures were poorly associated with ADL and IADL decline amongst older inpatients.
Morbidity measures are poor predictors for ADL or IADL decline amongst older inpatients and follow-up duration does not alter the performance of morbidity measures.
老年人常患有多种疾病,这会导致住院。这些疾病往往与健康结果不佳相关,如功能依赖和死亡率。本综述的目的是总结目前关于疾病负担衡量标准预测住院患者日常生活活动(ADL)和工具性日常生活活动(IADL)能力的文献。
使用 Medline、Cochrane、Embase 和 Cinahl Central 这四个数据库从建库至 2019 年 3 月 6 日进行了系统的文献检索。关键词包括合并症、多种疾病、ADL 和 IADL,以及特定的疾病负担衡量标准。纳入了报告疾病负担衡量标准预测 65 岁及以上住院患者 ADL 和 IADL 下降的文章。
在 7334 篇独特的文章中,有 12 篇文章纳入了 7826 名住院患者(平均年龄 77.6 岁,女性占 52.7%)。在五种疾病负担衡量标准中,Charlson 合并症指数最常被报告。总体而言,疾病负担衡量标准与老年住院患者的 ADL 和 IADL 下降相关性较差。
疾病负担衡量标准是预测老年住院患者 ADL 或 IADL 下降的不良指标,随访时间并不会改变疾病负担衡量标准的性能。