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放射性皮肤损伤:发病机制、治疗和管理。

Radiation-induced skin injury: pathogenesis, treatment, and management.

机构信息

Department of Radiation Oncology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China.

Department of Orthopedics, Shanghai Pudong Hospital, Fudan University, Pudong Medical Center, Shanghai, China.

出版信息

Aging (Albany NY). 2020 Nov 16;12(22):23379-23393. doi: 10.18632/aging.103932.

Abstract

Radiation-induced skin injury (RSI) refers to a frequently occurring complication of radiation therapy. Nearly 90% of patients having received radiation therapy underwent moderate-to-severe skin reactions, severely reducing patients' quality of life and adversely affecting their disease treatment. No gold standard has been formulated for RSIs. In the present study, the mechanism of RSI and topical medications was discussed. Besides, this study can be referenced for clinicians to treat RSIs to guide subsequent clinical medicine.

摘要

放射性皮肤损伤(RSI)是放疗中常见的并发症。近 90%接受放疗的患者出现中重度皮肤反应,严重降低了患者的生活质量,对疾病治疗产生不利影响。目前尚未制定 RSI 的金标准。本研究探讨了 RSI 的发病机制和局部药物治疗。此外,本研究可为临床医生治疗 RSI 提供参考,以指导后续临床医学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0302/7746368/a005348f2b5f/aging-12-103932-g001.jpg

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