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[Effect of diltiazem on blood cyclosporin levels].

作者信息

Kunzendorf U, Walz G, Neumayer H H, Wagner K, Keller F, Offermann G

机构信息

Freie Universität Berlin, Klinikum Steglitz, Medizinische Klinik.

出版信息

Klin Wochenschr. 1987 Nov 16;65(22):1101-3. doi: 10.1007/BF01736117.

DOI:10.1007/BF01736117
PMID:3320488
Abstract

The simultaneous administration of the calcium channel blocker diltiazem and cyclosporin results in a significant increase of RIA cyclosporin blood levels. The HPLC cyclosporin levels are not influenced.

摘要

相似文献

1
[Effect of diltiazem on blood cyclosporin levels].
Klin Wochenschr. 1987 Nov 16;65(22):1101-3. doi: 10.1007/BF01736117.
2
Cyclosporin-diltiazem interaction: comparison of cyclosporin levels measured with two monoclonal antibodies.环孢素与地尔硫䓬的相互作用:用两种单克隆抗体测量环孢素水平的比较
Transplant Proc. 1989 Feb;21(1 Pt 2):1460-1.
3
Pharmacokinetic interaction between cyclosporin and diltiazem.环孢素与地尔硫䓬之间的药代动力学相互作用。
Eur J Clin Pharmacol. 1990;38(3):237-42. doi: 10.1007/BF00315023.
4
Cyclosporin A (CsA): pharmacokinetics, clinical monitoring and pharmacodynamics in bone marrow transplantation (BMT).环孢素A(CsA):骨髓移植(BMT)中的药代动力学、临床监测及药效学
Prog Clin Biol Res. 1989;309:325-32.
5
Summary on therapeutic drug monitoring for renal transplantation.肾移植治疗药物监测综述
Transplant Proc. 1990 Jun;22(3):1348-51.
6
Effect of diltiazem in the prevention of acute tubular necrosis, acute rejection, and cyclosporine levels.地尔硫䓬在预防急性肾小管坏死、急性排斥反应及环孢素血药浓度方面的作用。
Transplant Proc. 1991 Oct;23(5):2383-4.
7
A prospective study of the effect of diltiazem in renal allograft recipients receiving cyclosporine A: preliminary results.地尔硫䓬对接受环孢素A的肾移植受者影响的前瞻性研究:初步结果。
Transplant Proc. 1990 Oct;22(5):2127-8.
8
Prevention of posttransplant acute tubular necrosis by the calcium antagonist diltiazem: a prospective randomized study.钙拮抗剂地尔硫䓬预防移植后急性肾小管坏死:一项前瞻性随机研究。
Am J Nephrol. 1987;7(4):287-91. doi: 10.1159/000167487.
9
Effect of the calcium channel blocker diltiazem on cyclosporine A blood levels and dose requirements.钙通道阻滞剂地尔硫䓬对环孢素A血药浓度及剂量需求的影响。
Transplant Proc. 1988 Apr;20(2 Suppl 2):572-4.
10
[Protective effect of the calcium antagonist diltiazem on acute kidney failure following kidney transplantation. The results of a prospective randomized study].
Dtsch Med Wochenschr. 1986 Sep 5;111(36):1363-7. doi: 10.1055/s-2008-1068635.

引用本文的文献

1
Antihypertensive treatment for kidney transplant recipients.肾移植受者的降压治疗
Cochrane Database Syst Rev. 2009 Jul 8;2009(3):CD003598. doi: 10.1002/14651858.CD003598.pub2.
2
Diltiazem. A reappraisal of its pharmacological properties and therapeutic use.地尔硫䓬。对其药理特性和治疗用途的重新评估。
Drugs. 1990 May;39(5):757-806. doi: 10.2165/00003495-199039050-00009.

本文引用的文献

1
A radioimmunoassay to measure cyclosporin A in plasma and serum samples.一种用于测量血浆和血清样本中环孢素A的放射免疫分析方法。
J Immunoassay. 1981;2(1):19-32. doi: 10.1080/01971528108062989.
2
Simplified liquid-chromotographic analysis for cyclosporin A, and comparison with radioimmunoassay.
Clin Chem. 1983 Jan;29(1):180-3.
3
Cyclosporine and ketoconazole.环孢素和酮康唑。
Transplantation. 1984 Feb;37(2):214-15.
4
Inhibition of hepatic microsomal drug metabolism by the calcium channel blockers diltiazem and verapamil.钙通道阻滞剂地尔硫䓬和维拉帕米对肝微粒体药物代谢的抑制作用。
Biochem Pharmacol. 1985 Jul 15;34(14):2549-53. doi: 10.1016/0006-2952(85)90541-6.
5
Nephrotoxic and immunosuppressive potentials of cyclosporine metabolites in rats.
Transplant Proc. 1986 Dec;18(6 Suppl 5):41-5.
6
Biotransformation and distribution in blood of cyclosporine and its metabolites.环孢素及其代谢产物在血液中的生物转化与分布。
Transplant Proc. 1986 Dec;18(6 Suppl 5):25-34.
7
Exacerbation of cyclosporine toxicity by concomitant administration of erythromycin.同时使用红霉素会加重环孢素的毒性。
Transplantation. 1987 Feb;43(2):263-70. doi: 10.1097/00007890-198702000-00020.
8
In vitro immunosuppressive properties of cyclosporine metabolites.环孢素代谢产物的体外免疫抑制特性。
Transplantation. 1987 Jan;43(1):123-7. doi: 10.1097/00007890-198701000-00027.