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[咳嗽的病理生理学与治疗:病因学方法]

[Physiopathology and treatment of cough: an etiological approach].

作者信息

Christe Anna, Prella Maura, Schweizer Valérie, Janssens Jean-Paul

机构信息

Service de pneumologie, CHUV, 1011 Lausanne.

Service d'oto-rhino-laryngologie, CHUV, 1011 Lausanne.

出版信息

Rev Med Suisse. 2020 Nov 18;16(715):2204-2210.

Abstract

Chronic cough is a common symptom in the consultation of any general practitioner. It may be idiopathic or reflect a chronic disease. However, cough can become excessive, occurring in response to stimuli that do not usually cause this symptom. This entity is called Cough hypersensitivity syndrome (CHS). Its treatment involves the use of neuromodulator substances that specifically target this hypersensitivity, while maintaining intact the cough reflex, essential for protecting the airways. This review aims to present the current knowledge about the pathophysiology of chronic cough, the initial diagnostic approach that this symptom requires and cough treatments either available or in development.

摘要

慢性咳嗽是任何全科医生门诊中常见的症状。它可能是特发性的,也可能反映一种慢性疾病。然而,咳嗽可能会变得过度,对通常不会引起这种症状的刺激产生反应。这种情况被称为咳嗽高敏综合征(CHS)。其治疗涉及使用专门针对这种高敏反应的神经调节物质,同时保持对保护气道至关重要的咳嗽反射完整。本综述旨在介绍有关慢性咳嗽病理生理学的当前知识、该症状所需的初始诊断方法以及现有的或正在研发的咳嗽治疗方法。

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