Horovitz Tamir, Clementoni Matteo Tretti, Artzi Ofir
Department of Dermatology and Venereology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
Laserplast Aesthetic Medicine Center, Milan, Italy.
J Cosmet Dermatol. 2021 Jan;20(1):99-104. doi: 10.1111/jocd.13851. Epub 2020 Dec 2.
Many modalities have been described for the treatment of periorbital wrinkling.
The purpose of this study is to quantify the improvement of periorbital wrinkling achieved by current nonablative modalities, using a fractional 1565 nm Er:glass fiber laser.
Our study is a retrospective two-center case series including 16 patients treated with nonablative laser for periorbital wrinkling at the Tel-Aviv Sourasky Medical Center in Israel and Laserplast Aesthetic Medicine Center in Italy between 2017 and 2019. Patients were assessed for objective and subjective improvement, patient satisfaction, side effect profile, and downtime.
Improvement in average Fitzpatrick Wrinkle Scale scores (from 4.3 to 2.7 by ranking physician 1 and 3.8 to 2.4 by ranking physician 2, P < .001) was observed after 8 weeks. Global Assessment Improvement Scale scores were 2.6 (physician 1) and 2.2 (physician 2) on average. This correlated to mild-moderate subjective sense of improvement by patients. Side effects and downtime were minimal.
Our study suggests that current nonablative laser skin resurfacing technology offers a mild-moderate improvement in periorbital wrinkling.
已经描述了多种治疗眶周皱纹的方法。
本研究的目的是使用1565纳米分数倍掺铒玻璃光纤激光，量化当前非剥脱性方法治疗眶周皱纹所取得的改善效果。
我们的研究是一项回顾性双中心病例系列研究，纳入了2017年至2019年间在以色列特拉维夫索拉斯基医疗中心和意大利激光整形美容医学中心接受非剥脱性激光治疗眶周皱纹的16例患者。对患者进行客观和主观改善情况、患者满意度、副作用情况及停工期的评估。
8周后观察到平均菲茨帕特里克皱纹量表评分有所改善（评级医生1从4.3降至2.7，评级医生2从3.8降至2.4，P <.001）。全球评估改善量表评分平均为2.6（医生1）和2.2（医生2）。这与患者轻度至中度的主观改善感觉相关。副作用和停工期 minimal。
我们的研究表明，当前的非剥脱性激光皮肤重建技术可使眶周皱纹得到轻度至中度改善。
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