Yasuda K, Sakuma M, Goh K, Okude J, Tanabe T, Kondo N, Yoshiki T
Second Department of Surgery, Hokkaido University, School of Medicine, Sapporo, Japan.
Nihon Geka Gakkai Zasshi. 1987 Oct;88(10):1503-8.
Two cases of "Inflammatory" aneurysm of the abdominal aorta and a review of this type of lesion were presented. The incidence of inflammatory aneurysm of the abdominal aorta in the literature is 2.5 to 15%, but there were no detail reports concerning with this in Japan. The pathogenesis is not clear, but it is evident both macroscopically and microscopically that the inflammatory aneurysms are different from athelosclerotic ones. They are characterized by perivascular peel of inflammatory fibrous tissue. It is possible that this type of aneurysms are merely a variant of Takayasu's disease. Until recently, the diagnosis of this type of aneurysm has not been made before surgery. The symptom of abdominal pain, weight loss, elevated ESR in a patient with abdominal aortic aneurysm are highly suggestive an inflammatory aneurysm. Characteristics of CT scan lead to more frequent preoperative diagnosis of inflammatory aneurysms of the aorta. It reveals a thickened often calcified aortic wall surrounded by a soft tissue mantle. Dynamic scanning shows an enhancing perianeurysnal mass. Graft replacement in these patients is often difficult and associated with increase in morbidity and mortality. At surgery, no attempt should be made to mobilize adjacent viscela in order to avoid injury. Arterial control should be obtained with as little as possible dissection. Some reports refer to successful steroid therapy resolving the inflammatory process and alleviating symptoms. Further research may resolve the treatment of choice for this type of lesion and optimize the timing of surgery.
本文报告了2例腹主动脉“炎性”动脉瘤病例,并对该类型病变进行了综述。文献中腹主动脉炎性动脉瘤的发病率为2.5%至15%,但日本尚无关于此的详细报道。其发病机制尚不清楚,但在宏观和微观上,炎性动脉瘤均明显不同于动脉粥样硬化性动脉瘤。它们的特征是血管周围有炎性纤维组织包膜。这种类型的动脉瘤可能仅仅是高安氏病的一种变体。直到最近,这类动脉瘤在手术前还无法诊断。腹主动脉瘤患者出现腹痛、体重减轻、血沉升高的症状,高度提示为炎性动脉瘤。CT扫描的特征使得术前更频繁地诊断出主动脉炎性动脉瘤。它显示主动脉壁增厚,常伴有钙化,周围有软组织包膜。动态扫描显示动脉瘤周围有强化肿块。这些患者的血管移植置换往往很困难,且与发病率和死亡率增加相关。手术时,不应试图游离邻近脏器以免造成损伤。应尽可能减少解剖以控制动脉。一些报告提到类固醇疗法成功地解决了炎症过程并缓解了症状。进一步的研究可能会确定这类病变的最佳治疗方法并优化手术时机。