From the Departments of Radiology and Imaging Sciences.
Pathology and Laboratory Medicine, Emory University School of Medicine.
Clin Nucl Med. 2021 May 1;46(5):e282-e285. doi: 10.1097/RLU.0000000000003408.
18F-Fluciclovine is an amino acid-based radiopharmaceutical used primarily for PET imaging of patients with biochemical recurrence of prostate cancer. We report a case of a 66-year-old man with recently diagnosed metastatic castrate-resistant prostate cancer and a left supraclavicular lymph node with incidental radiotracer uptake on 18F-fluciclovine PET/CT. Left neck core needle biopsy confirmed high-grade, poorly differentiated carcinoma with neuroendocrine features positive for synaptophysin and chromogranin, and negative for prostate markers.
18F-氟代脱氧葡萄糖是一种用于正电子发射断层扫描（PET）成像的氨基酸类放射性药物，主要用于生化复发前列腺癌患者的检测。我们报告了一例 66 岁男性，最近被诊断患有转移性去势抵抗性前列腺癌，左锁骨上淋巴结在 18F-氟代脱氧葡萄糖 PET/CT 上有放射性示踪剂摄取的偶然发现。左颈部核心针活检证实为高级别、低分化癌，具有神经内分泌特征，突触素和嗜铬粒蛋白阳性，前列腺标志物阴性。
