Krayevsky A A, Kukhanova M K, Beabealashvilli R Sh, Chidgeavadze Z G
Institute of Molecular Biology, USSR Academy of Sciences, Moscow.
Nucleic Acids Symp Ser. 1987(18):121-4.
The group of DNA polymerases was studied using some new nucleoside 5'-triphosphate analogs with termination substrate properties. Among DNA polymerases tested the least specific appeared reverse transcriptases of retroviruses and the most specific were DNA polymerases alpha type from high eucaryotes including mammalians.
利用一些具有终止底物特性的新型核苷 5'-三磷酸类似物对 DNA 聚合酶组进行了研究。在所测试的 DNA 聚合酶中,特异性最低的是逆转录病毒的逆转录酶,而特异性最高的是包括哺乳动物在内的高等真核生物的α型 DNA 聚合酶。