Alkhaldy Husain Y, Hadi Rawan A, Alghamdi Khalid A, Alqahtani Saleh M, Al Jabbar Ibraheem Sultan H, Al Ghamdi Ibrahim S, Bakheet Omayma Saad E, Saleh Rayyh A M, Shehata Shehata F, Aziz Shahid
Department of Internal Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Department of Laboratory Medicine and Blood Bank, Aseer Central Hospital, Abha, Kingdom of Saudi Arabia.
J Family Med Prim Care. 2020 Sep 30;9(9):5018-5025. doi: 10.4103/jfmpc.jfmpc_730_20. eCollection 2020 Sep.
The prevalence of iron deficiency, latent and symptomatic, is heterogeneous worldwide. In this study, we aim to explore the prevalence of iron deficiency, with and without anemia, among medical college females at the high Altitude Aseer region of Southwestern Saudi Arabia.
200 female medical students were randomly sampled, between the ages of 19 and 27 years. Blood samples were collected for complete blood count (CBC) values and serum ferritin determination. Questionnaires were completed in order to collect demographics, medical history, and socioeconomic information of the participants.
Prevalence of overall iron deficiency was high (63%, serum ferritin <20 μg/L, 52.5%, ferritin <15 μg/L). Anemia, adjusted for high altitude (defined as less than 13 g/dL was present in 41 participants (20.5%) and 12 (6.5%) have Hb <12 g/dL. Iron-deficiency anemia (Hb <13 g/dL and serum ferritin <15 μg/L) was present in 35 (17.5%). Personal and family history of anemia and poor animal product containing meals were positively correlated with the presence of iron deficiency state. Neither symptoms of anemia, nor the presence of menorrhagia correlate with the presence of iron deficiency anemia.
Iron deficiency with and without anemia is a very common and condition in young females' population at high altitude. Implementing a lab method to screen for anemia on vulnerable populations is needed. Frequently asymptomatic, the primary care providers should maintain a high degree of suspicion in order to initiate screening for iron status.
缺铁(包括潜在性缺铁和症状性缺铁)在全球范围内的患病率存在差异。在本研究中,我们旨在探讨沙特阿拉伯西南部高海拔阿西尔地区医学院女性中缺铁(无论是否伴有贫血)的患病率。
随机抽取200名年龄在19至27岁之间的女性医学生。采集血样以测定全血细胞计数(CBC)值和血清铁蛋白。完成问卷调查以收集参与者的人口统计学、病史和社会经济信息。
总体缺铁患病率较高(血清铁蛋白<20μg/L时为63%,铁蛋白<15μg/L时为52.5%)。经高海拔因素校正后的贫血(定义为血红蛋白低于13g/dL)在41名参与者中出现(20.5%),12名(6.5%)血红蛋白<12g/dL。缺铁性贫血(血红蛋白<13g/dL且血清铁蛋白<15μg/L)存在于35名(17.5%)参与者中。个人和家族贫血史以及动物性食品摄入不足与缺铁状态呈正相关。贫血症状和月经过多均与缺铁性贫血的存在无关。
无论是否伴有贫血,缺铁在高海拔地区年轻女性人群中是一种非常常见的情况。需要采用实验室方法对易感人群进行贫血筛查。由于缺铁通常无症状,初级保健提供者应保持高度怀疑,以便启动铁状态筛查。