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[十二指肠乳头良性肿瘤的诊断与治疗]

[Diagnosis and treatment of benign neoplasms of the major duodenal papilla].

作者信息

Teterin Yu S, Yartsev P A, Rogal M L, Tigiev L R, Shavrina N V, Nugumanova K A, Stepan E V

机构信息

Sklifosovsky Research Institute for Emergency Care, Moscow, Russia.

出版信息

Khirurgiia (Mosk). 2020(11):32-36. doi: 10.17116/hirurgia202011132.

DOI:10.17116/hirurgia202011132
PMID:33210505
Abstract

OBJECTIVE

To evaluate an efficacy of surgical treatment of patients with benign tumors of the major duodenal papilla.

MATERIAL AND METHODS

For the period from January 2015 to January 2020, sixteenth patients with benign tumors of the major duodenal papilla were treated at the Sklifosovsky Research Institute for Emergency Care. There were 7 men (43.7%) and 9 women (56.3%). Tumor dimension ranged from 1.0 to 4.0 cm (mean 2.5 cm).

RESULTS AND DISCUSSION

Tumor resection through laparotomy was performed in 4 (25%) patients. Six (37.5%) patients underwent endoscopic submucosal papillectomy. Other 6 (37.5%) patients refused surgical treatment due to regression of symptoms. Postoperative re-laparotomy was performed in 1 patient (10%) with acute perforated duodenal ulcer. There were no complications after endoscopic papillectomy. Control endoscopic examination identified no signs of tumor recurrence in all patients after 3 and 6 months. In our opinion, endoscopic papillectomy is preferable for adenoma of the major duodenal papilla due to reduced surgical trauma. We assume that stenting of the bile ducts and the major pancreatic duct prevented acute pancreatitis and obstructive jaundice.

CONCLUSION

Endoscopic papillectomy is an effective minimally invasive treatment of tumors of the major duodenal papilla. Despite a considerable number of complications, most of them can be resolved by conservative treatment or endoscopic procedures. Thus, endoscopic papillectomy may be considered as preferable method in the treatment of patients with benign tumors of the major duodenal papilla.

摘要

目的

评估十二指肠乳头良性肿瘤患者的手术治疗效果。

材料与方法

2015年1月至2020年1月期间,斯克利福索夫斯基急救研究所收治了16例十二指肠乳头良性肿瘤患者。其中男性7例(43.7%),女性9例(56.3%)。肿瘤大小为1.0至4.0厘米(平均2.5厘米)。

结果与讨论

4例(25%)患者通过开腹手术进行肿瘤切除。6例(37.5%)患者接受了内镜下黏膜乳头切除术。另外6例(37.5%)患者因症状缓解而拒绝手术治疗。1例(10%)十二指肠急性穿孔患者接受了术后再次开腹手术。内镜乳头切除术后无并发症发生。术后3个月和6个月的对照内镜检查显示,所有患者均无肿瘤复发迹象。我们认为,内镜乳头切除术因手术创伤较小,更适合十二指肠乳头腺瘤。我们推测,胆管和主胰管支架置入预防了急性胰腺炎和梗阻性黄疸。

结论

内镜乳头切除术是十二指肠乳头肿瘤有效的微创治疗方法。尽管存在相当数量的并发症,但大多数可通过保守治疗或内镜手术解决。因此,内镜乳头切除术可被视为治疗十二指肠乳头良性肿瘤患者的首选方法。

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