MOE Key Laboratory of Macromolecular Synthesis and Functionalization, and Key Laboratory of Adsorption and Separation Materials & Technologies of Zhejiang Province, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China.
School of Materials Science and Engineering, Zhejiang Sci-Tech University, 928 Second Avenue, Xiasha Higher Education Park, Hangzhou 310018, China.
Nano Lett. 2020 Dec 9;20(12):8760-8767. doi: 10.1021/acs.nanolett.0c03632. Epub 2020 Nov 19.
Organic solvent nanofiltration (OSN) is regarded as a promising separation technology in chemical and pharmaceutical industries. However, it remains a great challenge in fabricating OSN membranes with high permeability and precise selectivity by simple, transfer-free, and up-scalable processes. Herein, we report lysozyme nanofilm composite membranes (LNCM) prepared by one-step methods with hydrophobic substrates at the air/water interface. The microporous substrates not only promote the heterogeneous nucleation of amyloid-like lysozyme oligomers to construct small pores in the formed nanofilms but also benefit for the simultaneous composition of LNCM via hydrophobic interactions. The constructed nanopores are reduced to around 1.0 nm, and they are demonstrated by grazing incidence small-angle X-ray scattering with a closely packed model. The LNCM can tolerate most organic polar solvents and the permeability surpasses most of state-of-the-art OSN membranes.
有机溶剂纳滤（OSN）被认为是化学和制药行业中很有前途的分离技术。然而，通过简单、无转移和可扩展的工艺来制造具有高渗透性和精确选择性的 OSN 膜仍然是一个巨大的挑战。在此，我们报告了通过在空气/水界面处的一步法用疏水性基底制备溶菌酶纳米膜复合膜（LNCM）。微孔基底不仅促进了类似淀粉样的溶菌酶低聚物的异相成核，以在形成的纳滤膜中构建小孔，而且还通过疏水性相互作用有利于 LNCM 的同时组成。所构建的纳米孔减小到约 1.0nm，并通过小角 X 射线散射（具有紧密堆积模型）进行了证实。LNCM 可以耐受大多数有机极性溶剂，其渗透性超过了大多数最先进的 OSN 膜。
