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产后抑郁症在埃塞俄比亚的流行病学:系统评价和荟萃分析。

The epidemiology of postnatal depression in Ethiopia: a systematic review and meta-analysis.

机构信息

Faculty of Heath Sciences, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.

School of Public Health, Curtin University, Perth, Australia.

出版信息

Reprod Health. 2020 Nov 19;17(1):180. doi: 10.1186/s12978-020-01035-1.

Abstract

BACKGROUND

Postnatal depression is among the common mental health problems that occur during the postnatal period. However, it is left undiagnosed in low- and middle-income countries including Ethiopia. Therefore, this systematic review and meta-analysis aimed to systematically summarize the available evidence on the epidemiology of postnatal depression in Ethiopia and suggest recommendations for future clinical practice.

METHODS

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was followed to conduct this systematic review and meta-analysis. We searched PubMed, SCOPUS, EMBASE and Google Scholar databases for the relevant articles that assessed the prevalence of postnatal depression in Ethiopia. We used a random-effect model to conduct a meta-analysis. We conducted a subgroup and sensitivity analysis to explore the source of heterogeneity. Cochrane Q- and the I-test were used to check the heterogeneity of the included studies. The presence of publication bias was also checked by visual inspection of symmetry and Egger's test.

RESULTS

The pooled estimated prevalence of postnatal depression in Ethiopia was 20.1% (95% CI 12.7-30.2). The pooled prevalence of postnatal depression in the studies that were conducted in community settings and used the Patient Health Questionnaire to assess postnatal depression [16.6% (95% CI 8.90-28.99)] was lower than the prevalence in studies based in institutions and that used the Edinburgh Postnatal Depression Scale [23.2% (95% CI 14.50-28.5)]. Further, in a leave-one-out sensitivity analysis the prevalence of postnatal depression ranges between 15.4% and 25.4%. Unplanned pregnancy [AOR = 3.46, 95% CI (2.37-5.04)], age between 15-24 years [AOR = 1.72, 95% CI (1.11-2.68)], marital problems [AOR = 3.07, 95% CI (2.36-3.99)], experiencing the death of infant [AOR = 3.41, 95% CI (1.91-6.09)] and history of substance use [AOR = 3.47, 95% CI (2.17-5.56)] were associated with the increased odds of postnatal depression in Ethiopia.

CONCLUSION

The prevalence of postnatal depression in Ethiopia was high. Therefore, the concerned body should give due attention to improve reproductive health services through early detection of risk factors of postnatal depression.

摘要

背景

产后抑郁症是产后常见的心理健康问题之一。然而,在包括埃塞俄比亚在内的低收入和中等收入国家,这种疾病常常未被诊断出来。因此,本系统评价和荟萃分析旨在系统总结埃塞俄比亚产后抑郁症的现有证据,并为未来的临床实践提供建议。

方法

本系统评价和荟萃分析遵循了《系统评价和荟萃分析的首选报告项目》(PRISMA)指南。我们检索了 PubMed、SCOPUS、EMBASE 和 Google Scholar 数据库,以获取评估埃塞俄比亚产后抑郁症患病率的相关文章。我们使用随机效应模型进行荟萃分析。我们进行了亚组和敏感性分析,以探讨异质性的来源。Cochrane Q 检验和 I 检验用于检查纳入研究的异质性。还通过视觉检查对称性和 Egger 检验检查发表偏倚的存在。

结果

埃塞俄比亚产后抑郁症的总估计患病率为 20.1%(95%CI 12.7-30.2)。在社区环境中进行且使用患者健康问卷评估产后抑郁症的研究中,产后抑郁症的总患病率为 16.6%(95%CI 8.90-28.99),低于在机构中进行且使用爱丁堡产后抑郁量表评估产后抑郁症的研究中的患病率 23.2%(95%CI 14.50-28.5)。此外,在逐一剔除敏感性分析中,产后抑郁症的患病率在 15.4%至 25.4%之间变化。非计划性怀孕[OR=3.46,95%CI(2.37-5.04)]、年龄在 15-24 岁[OR=1.72,95%CI(1.11-2.68)]、婚姻问题[OR=3.07,95%CI(2.36-3.99)]、婴儿死亡[OR=3.41,95%CI(1.91-6.09)]和物质使用史[OR=3.47,95%CI(2.17-5.56)]与埃塞俄比亚产后抑郁症的发病风险增加有关。

结论

埃塞俄比亚产后抑郁症的患病率很高。因此,有关部门应重视通过早期发现产后抑郁症的危险因素来改善生殖健康服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d94/7678214/894e65e487cf/12978_2020_1035_Fig1_HTML.jpg

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