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药物诱导的娱乐性阴茎异常勃起:病例报告与综述

Pharmacologically-induced Recreational Priapism: Case Report and Review.

作者信息

Kunas Grace, Smereck Janet A, Ladkany Diana, Davis Jonathan E

机构信息

Abrazo Health, Department of Emergency Medicine, Goodyear, Arizona.

Georgetown University Medical Center, Department of Emergency Medicine, Washington, District of Columbia.

出版信息

Clin Pract Cases Emerg Med. 2020 Nov;4(4):591-594. doi: 10.5811/cpcem.2020.8.47763.

DOI:10.5811/cpcem.2020.8.47763
PMID:33217280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7676772/
Abstract

INTRODUCTION

Priapism, a time-sensitive urologic emergency, is associated with hematologic disorders, malignancies, trauma, pharmaceuticals, and recreational drugs.

CASE REPORT

A 51-year-old male presented with 36 hours of priapism after recreational use of nonprescribed pharmaceuticals including an oral phosphodiesterase inhibitor and intracorporally injected erectile medications, together with unspecified quantities of cocaine and alcohol. Venous blood gas confirmed ischemic priapism. Detumescence was achieved with intracavernosal phenylephrine injection, aspiration, and irrigation.

CONCLUSION

This case highlights the risk that recreational use of vasoactive medications by patients who seek to prolong sexual activity may lead to delayed presentation for ischemic priapism.

摘要

引言

阴茎异常勃起是一种对时间敏感的泌尿外科急症,与血液系统疾病、恶性肿瘤、创伤、药物及消遣性药物有关。

病例报告

一名51岁男性在非处方使用包括口服磷酸二酯酶抑制剂和阴茎海绵体内注射勃起药物在内的药物、以及未明确用量的可卡因和酒精后,出现了36小时的阴茎异常勃起。静脉血气分析证实为缺血性阴茎异常勃起。通过阴茎海绵体内注射去氧肾上腺素、抽吸和冲洗实现了消肿。

结论

该病例凸显了试图延长性活动时间的患者消遣性使用血管活性药物可能导致缺血性阴茎异常勃起延迟就诊的风险。

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本文引用的文献

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Priapism associated with pregabalin.与普瑞巴林相关的阴茎异常勃起。
Am J Emerg Med. 2020 Apr;38(4):852.e1-852.e2. doi: 10.1016/j.ajem.2019.11.027. Epub 2019 Nov 30.
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Priapism induced by use of tamsulosin: A case report and review of the literature.坦索罗辛所致阴茎异常勃起:一例病例报告及文献复习
Arch Ital Urol Androl. 2019 Oct 2;91(3). doi: 10.4081/aiua.2019.3.193.
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Treatment of Priapism Secondary to Drugs for Erectile Dysfunction.治疗药物性勃起功能障碍所致的阴茎异常勃起
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Priapism from Recreational Intracavernosal Injections in a High-Risk Metropolitan Community.高危都市社区中娱乐性海绵体内注射导致的阴茎异常勃起。
J Sex Med. 2019 Oct;16(10):1650-1654. doi: 10.1016/j.jsxm.2019.07.024. Epub 2019 Sep 6.
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Priapism caused by 'Tribulus terrestris'.因蒺藜引起的阴茎异常勃起。
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Ninety-six hours ordeal of priapism induced by paroxetine--A case report and literature review.帕罗西汀诱发阴茎异常勃起96小时的折磨——病例报告及文献综述
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Refractory priapism associated with ingestion of yohimbe extract.与育亨宾提取物摄入相关的难治性阴茎异常勃起。
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