Suppr超能文献

超治疗剂量华法林抗凝继发广泛上呼吸道血肿

Extensive Upper Airway Hematoma Secondary to Supratherapeutic Warfarin Anticoagulation.

作者信息

Oyedokun Taofiq Olusegun, Durr Kevin Manuel

机构信息

University of Saskatchewan, Department of Emergency Medicine, Saskatoon, Saskatchewan, Canada.

University of Ottawa, Department of Emergency Medicine, Ottawa, Ontario, Canada.

出版信息

Clin Pract Cases Emerg Med. 2020 Nov;4(4):634-635. doi: 10.5811/cpcem.2020.7.48695.

Abstract

CASE PRESENTATION

A 63-year-old female presented to the emergency department complaining of cough, neck swelling, dysphagia, and dysphonia for two days, with a past medical history of atrial fibrillation managed with warfarin. Investigations revealed a supratherapeutic international normalised ratio (greater than 10). Imaging and endoscopic examination showed an extensive retropharyngeal hematoma with significant mass effect on the airway.

DISCUSSION

A rare but potentially fatal complication of warfarin anticoagulation is upper airway hematoma, with violent coughing described as an inciting cause. Signs of airway compromise necessitate specialist consultation and definitive airway management, while mild cases without airway concerns can be managed conservatively with medical anticoagulation reversal.

摘要

病例介绍

一名63岁女性因咳嗽、颈部肿胀、吞咽困难和声音嘶哑两天就诊于急诊科,既往有房颤病史,正在接受华法林治疗。检查发现国际标准化比值高于治疗范围(大于10)。影像学和内镜检查显示广泛的咽后血肿,对气道有明显的占位效应。

讨论

华法林抗凝治疗罕见但可能致命的并发症是上气道血肿,剧烈咳嗽被认为是诱发原因。气道受压的体征需要专科会诊和确定气道管理方案,而无气道问题的轻症病例可通过药物抗凝逆转进行保守治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9488/7676778/cd93ff974000/cpcem-04-634-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验