Laurin J, Persson P H, Polberger S
Department of Gynaecology and Obstetrics, University of Lund, Malmö General Hospital, Sweden.
Acta Obstet Gynecol Scand. 1987;66(4):337-43. doi: 10.3109/00016348709103649.
To analyse the incidence of fetal growth retardation and its impact on perinatal mortality and neonatal morbidity, pregnancies complicated by intra-uterine growth retardation (IUGR) were compared with matched non-IUGR pregnancies. The IUGR group included all infants born in the city of Malmö during the study period and having a birthweight of 2 standard deviations or more below the mean birthweight for gestational age. The gestational age of all pregnancies was assessed with ultrasound in the first half of pregnancy. The IUGR fetuses were more vulnerable during delivery, and emergency cesarean section due to imminent fetal asphyxia was performed more frequently, but Apgar scores were similar in both groups. The frequency of respiratory disorders was lower in the IUGR group than in the non-IUGR group when corticosteroid-treated pregnancies were excluded. The IUGR group required slightly longer care on the neonatal ward than the non-IUGR group, but not more intervention. The IUGR group as a whole had an unexpectedly low neonatal complication rate, such complications as did occur being related to preterm birth rather than to growth retardation.
为分析胎儿生长受限的发生率及其对围产期死亡率和新生儿发病率的影响,将合并宫内生长受限(IUGR)的妊娠与匹配的非IUGR妊娠进行比较。IUGR组包括研究期间在马尔默市出生且出生体重低于孕周平均出生体重2个标准差或更多的所有婴儿。所有妊娠的孕周在妊娠前半期通过超声评估。IUGR胎儿在分娩期间更易出现问题,因即将发生胎儿窒息而进行急诊剖宫产的频率更高,但两组的阿氏评分相似。排除接受皮质类固醇治疗的妊娠后,IUGR组的呼吸系统疾病发生率低于非IUGR组。IUGR组在新生儿病房所需的护理时间略长于非IUGR组,但干预措施并不更多。IUGR组总体的新生儿并发症发生率出乎意料地低,所发生的此类并发症与早产有关,而非与生长受限有关。