龈沟液和种植体周袋液中 MMP-8 和 MMP-9 浓度的对比分析。
Comparative Analysis of MMP-8 and MMP-9 Concentrations in Crevicular and Peri-Implants Sulcular Fluids.
机构信息
Department of Orthopedic Dentistry, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.
A. I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation, Moscow, Russia.
出版信息
Bull Exp Biol Med. 2020 Nov;170(1):19-23. doi: 10.1007/s10517-020-04996-2. Epub 2020 Nov 21.
The concentrations of MMP-8 and MMP-9 were measured in the crevicular and the peri-implant sulcular fluids at the different stages of the prosthetic treatment. The concentration MMP-8 and MMP-9 in the peri-implant sulcular fluids were significantly higher (p<0.05) then in the gingival crevicular fluid. The determined parameters are the references values for dynamic observation over the functional state of the dental "implant-bone-soft" tissue system. The detected the correlations attest to synergy between secretion of MMP-8 and MMP-9 in the peri-implant sulcular fluid and allow analysis of the dependence of the secretion of these metalloproteinases on clinical and physiological peculiarities of the gingiva, which will help to better customize implant-supported prosthetic treatment of the patients.
在修复治疗的不同阶段，测量了龈沟液和种植体周围沟液中 MMP-8 和 MMP-9 的浓度。种植体周围沟液中 MMP-8 和 MMP-9 的浓度明显高于（p<0.05）龈沟液。确定的参数是对牙“种植体-骨-软组织”系统功能状态进行动态观察的参考值。检测到的相关性证明了种植体周围沟液中 MMP-8 和 MMP-9 的分泌协同作用，并允许分析这些金属蛋白酶分泌对牙龈临床和生理特性的依赖性，这将有助于更好地为患者定制种植体支持的修复治疗。
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