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纳米胶囊制备中 PBAT 含量的影响及其对精油释放的影响。

The influence of PBAT content in the nanocapsules preparation and its effect in essential oils release.

机构信息

Centro de Engenharia, Modelagem e Ciências Sociais Aplicadas - CECS/Universidade Federal do ABC (UFABC) - Santo André, Avenida dos Estados, 5001, CEP: 09210-580, SP, Brazil.

Department of Materials Science and Engineering, Tuskegee University, Tuskegee, AL 36088, USA.

出版信息

Food Chem. 2021 May 15;344:128611. doi: 10.1016/j.foodchem.2020.128611. Epub 2020 Nov 12.

Abstract

Nanoencapsulation provides new alternatives for the food industry, enabling a controlled and slow release of active antimicrobial agents, such as essential oils (EO). Poly (butylene adipate-co-terephthalate) (PBAT) nanocapsules loaded with linalool EO were prepared using an extrusion method with 1, 3, and 5% w/v (PBAT to chloroform). Nanocapsules' sizes ranged from 100 to 250 nm and were spherical. The release profile was studied using an ethanoic medium over 24 h, and according to the Korsmeyer-Peppas model, a Fick diffusion mechanism was involved. FT-IR and thermogravimetric analyses confirmed EO encapsulation with an encapsulation efficiency of 55%, 71%, and 74% for 1, 3, and 5%, respectively. The results indicated that encapsulation depended on organic phase concentration, with higher PBAT contents achieving better results. The resulting nanocapsules had antimicrobial activity against E. coli, which could be extended to develop active packaging systems.

摘要

纳米胶囊为食品工业提供了新的选择,能够控制和缓慢释放活性抗菌剂,如精油(EO)。使用挤出法,以 1、3 和 5%w/v(PBAT 与氯仿的比例)制备负载有芳樟醇精油的聚(丁二酸丁二醇酯-对苯二甲酸酯)(PBAT)纳米胶囊。纳米胶囊的尺寸在 100 至 250nm 之间,呈球形。使用醇酸介质在 24 小时内研究了释放曲线,根据 Korsmeyer-Peppas 模型,涉及菲克扩散机制。FT-IR 和热重分析证实了 EO 的包封,1、3 和 5%的包封效率分别为 55%、71%和 74%。结果表明,包封取决于有机相浓度,较高的 PBAT 含量可获得更好的效果。所得纳米胶囊对大肠杆菌具有抗菌活性,可进一步开发活性包装系统。

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